First published in 1981 by
Elsevier
Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', th ...
, ''Principles of Neural Science'' is an influential
neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, development ...
textbook
A textbook is a book containing a comprehensive compilation of content in a branch of study with the intention of explaining it. Textbooks are produced to meet the needs of educators, usually at educational institutions. Schoolbooks are textboo ...
edited by
Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
professors
Eric R. Kandel,
James H. Schwartz, and
Thomas M. Jessell. The original edition was 468 pages; now on the sixth edition, the book has grown to 1646 pages. The second edition was published in 1985, third in 1991, fourth in 2000. The fifth was published on October 26, 2012 and included Steven A. Siegelbaum and A.J. Hudspeth as editors. The sixth and latest edition was published on March 8, 2021.
Authors
Editors
* Kandel was one of the recipients of the
2000
File:2000 Events Collage.png, From left, clockwise: Protests against Bush v. Gore after the 2000 United States presidential election; Heads of state meet for the Millennium Summit; The International Space Station in its infant form as seen from ...
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...
. He is currently a professor of biochemistry, molecular biophysics, physiology, cellular biophysics, and psychiatry at
Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
. He is a senior investigator at the
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
and a recipient of the
National Medal of Science
The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social scienc ...
.
* Schwartz was a professor of physiology, cellular biophysics, neurology, and psychiatry at Columbia University.
* Jessell became an editor of the book starting from the third edition. He was a professor of biochemistry and molecular biophysics at Columbia University, and an investigator at the Howard Hughes Medical Institute.
* Hudspeth is a professor of sensory neuroscience at
Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
. He is also an investigator at the Howard Hughes Medical Institute.
* Siegelbaum is Chair of the Department of Neuroscience at Columbia University and is also an investigator at the Howard Hughes Medical Institute.
Contributors
Including the editors—all of whom also contributed to individual chapters in the book—there are a total of 45 authors of this text. Included among them are several notable researchers and physicians. Several authors are also highly decorated scientists, including
Nobel laureate
The Nobel Prizes ( sv, Nobelpriset, no, Nobelprisen) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make out ...
Linda B. Buck
Linda Brown Buck (born January 29, 1947) is an American biologist best known for her work on the olfactory system. She was awarded the 2004 Nobel Prize in Physiology or Medicine, along with Richard Axel, for their work on olfactory receptors. She ...
and renowned neurophysiologist
Roger M. Enoka
Roger Maro Enoka is professor and former chair of the Department of Integrative Physiology at the University of Colorado at Boulder. He is also the director of the Neurophysiology of Movement Lab.
According to Web of Knowledge, Professor Enoka ...
.
Content
''Principles of Neural Science'' is often assigned as a textbook for many
undergraduate
Undergraduate education is education conducted after secondary education and before postgraduate education. It typically includes all postsecondary programs up to the level of a bachelor's degree. For example, in the United States, an entry-lev ...
and
graduate/
medical
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practic ...
neuroscience and neurobiology courses. The book attempts to at least introduce every aspect of our most modern understanding of the
brain
A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a v ...
. The sixth edition is divided into sixty-four chapters, organized into nine parts:
* Part I: ''Overall Perspective''
* Part II: ''
Cell
Cell most often refers to:
* Cell (biology), the functional basic unit of life
Cell may also refer to:
Locations
* Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery ...
and
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
of Cells of the
Nervous System
In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes th ...
''
* Part III: ''
Synaptic Transmission''
* Part IV: ''
Perception
Perception () is the organization, identification, and interpretation of sensory information in order to represent and understand the presented information or environment. All perception involves signals that go through the nervous system ...
''
* Part V: ''
Movement''
* Part VI: ''The Biology of
Emotion
Emotions are mental states brought on by neurophysiological changes, variously associated with thoughts, feelings, behavioral responses, and a degree of pleasure or displeasure. There is currently no scientific consensus on a definition. ...
,
Motivation
Motivation is the reason for which humans and other animals initiate, continue, or terminate a behavior at a given time. Motivational states are commonly understood as forces acting within the agent that create a disposition to engage in goal-dire ...
, and
Homeostasis
In biology, homeostasis (British English, British also homoeostasis) Help:IPA/English, (/hɒmɪə(ʊ)ˈsteɪsɪs/) is the state of steady internal, physics, physical, and chemistry, chemical conditions maintained by organism, living systems. Thi ...
''
* Part VII: ''
Development
Development or developing may refer to:
Arts
*Development hell, when a project is stuck in development
*Filmmaking, development phase, including finance and budgeting
*Development (music), the process thematic material is reshaped
* Photograph ...
and the Emergence of
Behavior
Behavior (American English) or behaviour (British English) is the range of actions and mannerisms made by individuals, organisms, systems or artificial entities in some environment. These systems can include other systems or organisms as wel ...
''
* Part VII: ''
Learning
Learning is the process of acquiring new understanding, knowledge, behaviors, skills, value (personal and cultural), values, attitudes, and preferences. The ability to learn is possessed by humans, animals, and some machine learning, machines ...
,
Memory
Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembered, ...
,
Language
Language is a structured system of communication. The structure of a language is its grammar and the free components are its vocabulary. Languages are the primary means by which humans communicate, and may be conveyed through a variety of met ...
and
Cognition
Cognition refers to "the mental action or process of acquiring knowledge and understanding through thought, experience, and the senses". It encompasses all aspects of intellectual functions and processes such as: perception, attention, thought, ...
''
* Part IX: ''
Diseases of the Nervous System''
References
Sources
* Kandel ER, Schwartz JH, Jessell TM 1991. ''Principles of Neural Science, 3rd ed.'' Appleton & Lange.
* Kandel ER, Schwartz JH, Jessell TM 2000. ''Principles of Neural Science, 4th ed.'' McGraw-Hill, New York.
* Kandel ER, Schwartz JH, Jessell TM 2012, Siegelbaum SA, Hudspeth AJ. ''Principles of Neural Science, 5th ed.'' McGraw-Hill, New York.
* Kandel ER, Koester JD, Mack SH 2021, Siegelbaum SA. ''Principles of Neural Science, 6th ed.'' McGraw-Hill, New York. ISBN 978-1-25-964224-1
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