Pregnanediol Glucuronide
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Pregnanediol glucuronide, or 5β-pregnane-3α,20α-diol 3α-glucuronide, is the major metabolite of progesterone and the C3α
glucuronide A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond. The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucu ...
conjugate of pregnanediol (5β-pregnane-3α,20α-diol). Approximately 15 to 30% of a
parenteral A route of administration in pharmacology and toxicology is the way by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. ...
dose of progesterone is
metabolized Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
into pregnanediol glucuronide. While this specific isomer is referred to as ''pregnanediol glucuronide'' and is the most major form, there are actually many possible isomers of the metabolite.


References

Diols Glucuronide esters Human metabolites Pregnanes {{Biochemistry-stub