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Praxagoras ( grc, Πραξαγόρας ὁ Κῷος) was a figure of
medicine in ancient Greece Ancient Greek medicine was a compilation of theories and practices that were constantly expanding through new ideologies and trials. Many components were considered in ancient Greek medicine, intertwining the spiritual with the physical. Specifi ...
. He was born on the
Greek Greek may refer to: Greece Anything of, from, or related to Greece, a country in Southern Europe: *Greeks, an ethnic group. *Greek language, a branch of the Indo-European language family. **Proto-Greek language, the assumed last common ancestor ...
island of
Kos Kos or Cos (; el, Κως ) is a Greek island, part of the Dodecanese island chain in the southeastern Aegean Sea. Kos is the third largest island of the Dodecanese by area, after Rhodes and Karpathos; it has a population of 36,986 (2021 census), ...
in about 340 BC. Both his father,
Nicarchus Nicarchus or Nicarch was a Greek poet and writer of the 1st century AD, best known for his epigrams, of which forty-two survive under his name in the ''Greek Anthology'', and his satirical poetry. He was a contemporary of, and influence on, the bet ...
, and his grandfather were physicians. Very little is known of Praxagoras' personal life, and none of his writings have survived.


History

Between the death of
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
in 375 BC and the founding of the school in
Alexandria Alexandria ( or ; ar, ٱلْإِسْكَنْدَرِيَّةُ ; grc-gre, Αλεξάνδρεια, Alexándria) is the second largest city in Egypt, and the largest city on the Mediterranean coast. Founded in by Alexander the Great, Alexandria ...
, Egypt, Greek medicine became entrenched with speculation, seeing little advances in medicine. During this period four men took up the study of anatomy:
Diocles of Carystus Diocles of Carystus (; el, Διοκλῆς ὁ Καρύστιος; la, Diocles Carystius; also known by the Latin name Diocles Medicus, i.e. "Diocles the physician"; c. 375 BC – c. 295 BC) was a well-regarded Greek physician, born in Carystus, a ...
(fl. 4th century BC),
Herophilus Herophilos (; grc-gre, Ἡρόφιλος; 335–280 BC), sometimes Latinised Herophilus, was a Greek physician regarded as one of the earliest anatomists. Born in Chalcedon, he spent the majority of his life in Alexandria. He was the first sci ...
(c. 335–280 BC),
Erasistratus Erasistratus (; grc-gre, Ἐρασίστρατος; c. 304 – c. 250 BC) was a Greek anatomist and royal physician under Seleucus I Nicator of Syria. Along with fellow physician Herophilus, he founded a school of anatomy in Alexandria, where the ...
(c. 304–250 BC), and finally Praxagoras.
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of ...
(AD 129–216), a famous Greek physician, wrote of Praxagoras as this influential figure in Greek medicine and a member of the logical or
Dogmatic school The Dogmatic school of medicine (''Dogmatics'', or ''Dogmatici'', el, Δογματικοί) was a school of medicine in ancient Greece and Rome. They were the oldest of the medical sects of antiquity. They derived their name from ''dogma'', a phi ...
. Galen also probably knew of the works of Praxagoras, writing on natural sciences, anatomy, causes and treatment of disease, and on acute diseases. Praxagoras adopted a variation of the
humoral theory Humorism, the humoral theory, or humoralism, was a system of medicine detailing a supposed makeup and workings of the human body, adopted by Ancient Greek and Roman physicians and philosophers. Humorism began to fall out of favor in the 1850s ...
, but instead of the
four humors Humorism, the humoral theory, or humoralism, was a system of medicine detailing a supposed makeup and workings of the human body, adopted by Ancient Greek and Roman physicians and philosophers. Humorism began to fall out of favor in the 1850s ...
(
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
,
phlegm Phlegm (; , ''phlégma'', "inflammation", "humour caused by heat") is mucus produced by the respiratory system, excluding that produced by the nasal passages. It often refers to respiratory mucus expelled by coughing, otherwise known as sputum ...
, yellow
bile Bile (from Latin ''bilis''), or gall, is a dark-green-to-yellowish-brown fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is produced continuously by the liver (liver bile ...
, and black bile) that most physicians held, he insisted on eleven. Like the other Greek physicians, he believed health and disease were controlled by the balance or imbalance of these humors. For example, if the proper amount of heat is present in the organism, the process of digestion is natural. Too little or too much heat will cause a rise in the other humors, which then produces certain disease conditions. He considered digestion to be a kind of
putrefaction Putrefaction is the fifth stage of death, following pallor mortis, algor mortis, rigor mortis, and livor mortis. This process references the breaking down of a body of an animal, such as a human, post-mortem. In broad terms, it can be viewed ...
or decomposition, an idea that was held until the 19th century. Praxagoras was also influential in the Alexandrian school in particular. After the death of
Alexander the Great Alexander III of Macedon ( grc, wikt:Ἀλέξανδρος, Ἀλέξανδρος, Alexandros; 20/21 July 356 BC – 10/11 June 323 BC), commonly known as Alexander the Great, was a king of the Ancient Greece, ancient Greek kingdom of Maced ...
(356–323 BC), Egypt fell to the hands of General
Ptolemy Claudius Ptolemy (; grc-gre, Πτολεμαῖος, ; la, Claudius Ptolemaeus; AD) was a mathematician, astronomer, astrologer, geographer, and music theorist, who wrote about a dozen scientific treatises, three of which were of importanc ...
, who established a modern university with the first great medical school of antiquity. Human dissection was practiced, mostly by Herophilus and Erasistratus; Praxagoras was Herophilus' teacher. Although the university in Alexandria and its massive library was destroyed by bands of conquerors, later Arabic physicians made the efforts to preserve some of the writings. After the fall of the
Byzantine Empire The Byzantine Empire, also referred to as the Eastern Roman Empire or Byzantium, was the continuation of the Roman Empire primarily in its eastern provinces during Late Antiquity and the Middle Ages, when its capital city was Constantinopl ...
, Greek scholars brought back Greek medicine to the medical schools of the Western
Renaissance The Renaissance ( , ) , from , with the same meanings. is a period in European history marking the transition from the Middle Ages to modernity and covering the 15th and 16th centuries, characterized by an effort to revive and surpass ideas ...
.


Praxagoras' theory of circulation

Praxagoras studied
Aristotle Aristotle (; grc-gre, Ἀριστοτέλης ''Aristotélēs'', ; 384–322 BC) was a Greek philosopher and polymath during the Classical period in Ancient Greece. Taught by Plato, he was the founder of the Peripatetic school of phil ...
's (384–322 BC)
anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its ...
and improved it by distinguishing between
artery An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pul ...
and
veins Veins are blood vessels in humans and most other animals that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are the pulmonary and umbilical veins, both of which carry oxygenated b ...
. He saw arteries as air tubes, similar to the
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
and
bronchi A bronchus is a passage or airway in the lower respiratory tract that conducts air into the lungs. The first or primary bronchi pronounced (BRAN-KAI) to branch from the trachea at the carina are the right main bronchus and the left main bronchus. ...
, which carried
pneuma ''Pneuma'' () is an ancient Greek word for "breath", and in a religious context for "spirit" or "soul". It has various technical meanings for medical writers and philosophers of classical antiquity, particularly in regard to physiology, and is a ...
, the mystic force of life.Pendergraph, Garland E. (1998) ''Handbook of Phlebotomy and Patient Service and Techniques''. Williams & Wilkins.
Arteries An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pul ...
took the breath of life from the
lungs The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of th ...
to the left side of the
heart The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide t ...
through the
aorta The aorta ( ) is the main and largest artery in the human body, originating from the left ventricle of the heart and extending down to the abdomen, where it splits into two smaller arteries (the common iliac arteries). The aorta distributes ...
to the
arteries An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pul ...
of the body. He believed the arteries stemmed from the
heart The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide t ...
, but the
veins Veins are blood vessels in humans and most other animals that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are the pulmonary and umbilical veins, both of which carry oxygenated b ...
came from the
liver The liver is a major Organ (anatomy), organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of proteins and biochemicals necessary for ...
. Veins carried
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
, which was created by digested food, to the rest of the body. The combination of blood and pneuma generated heat. As one of the humors, thick, cold phlegm gathered in the
arteries An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pul ...
would cause
paralysis Paralysis (also known as plegia) is a loss of motor function in one or more muscles. Paralysis can also be accompanied by a loss of feeling (sensory loss) in the affected area if there is sensory damage. In the United States, roughly 1 in 50 ...
. Also, he believed that
arteries An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pul ...
were the channels through which voluntary motion was given to the body, and that the cause of
epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical ...
was the blocking of the aorta by this same accumulation of
phlegm Phlegm (; , ''phlégma'', "inflammation", "humour caused by heat") is mucus produced by the respiratory system, excluding that produced by the nasal passages. It often refers to respiratory mucus expelled by coughing, otherwise known as sputum ...
.
Aristotle Aristotle (; grc-gre, Ἀριστοτέλης ''Aristotélēs'', ; 384–322 BC) was a Greek philosopher and polymath during the Classical period in Ancient Greece. Taught by Plato, he was the founder of the Peripatetic school of phil ...
, Diocles, and Praxogoras insisted that the heart was the central organ of intelligence and the seat of thought. Praxagoras differed with the others in that he believed the purpose of respiration was to provide nourishment for the psychic pneuma, rather than to cool the inner heat.


Arteries and pulse

Praxagoras' views on arteries were very influential in the development of physiology. Since the concept of
nerves A nerve is an enclosed, cable-like bundle of nerve fibers (called axons) in the peripheral nervous system. A nerve transmits electrical impulses. It is the basic unit of the peripheral nervous system. A nerve provides a common pathway for the e ...
did not exist, Praxagoras explained the movement of arteries to the fact that arteries get smaller and smaller, and then disappear. This disappearance caused movement, a fact now attributed to nerves. However, he speculated about the role of movement and was satisfied that he had found the answer of the center of vitality and energy. His pupil,
Herophilus Herophilos (; grc-gre, Ἡρόφιλος; 335–280 BC), sometimes Latinised Herophilus, was a Greek physician regarded as one of the earliest anatomists. Born in Chalcedon, he spent the majority of his life in Alexandria. He was the first sci ...
, actually discovered both sensory and
motor An engine or motor is a machine designed to convert one or more forms of energy into mechanical energy. Available energy sources include potential energy (e.g. energy of the Earth's gravitational field as exploited in hydroelectric power gen ...
nerves. Praxagoras was interested in pulse and was the first to direct attention to the importance of arterial pulse in diagnosis. He insisted that arteries pulsed by themselves and were independent of the heart. Herophilus refuted this doctrine in his treatise "On Pulses." In another area, Galen criticized Praxagoras for displaying too little care in anatomy. He suggested that Praxagoras did not arrive at his theories by dissection. The beliefs of Praxagoras held sway for centuries. For example, for nearly 500 years after his death, many still believed that arteries did not contain blood but pneuma. His most famous pupil,
Herophilus Herophilos (; grc-gre, Ἡρόφιλος; 335–280 BC), sometimes Latinised Herophilus, was a Greek physician regarded as one of the earliest anatomists. Born in Chalcedon, he spent the majority of his life in Alexandria. He was the first sci ...
, was instrumental in establishing the marvelous medical establishment at Alexandria.


See also

*
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of ...
*
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
*
William Harvey William Harvey (1 April 1578 – 3 June 1657) was an English physician who made influential contributions in anatomy and physiology. He was the first known physician to describe completely, and in detail, the systemic circulation and proper ...
*
Marcello Malpighi Marcello Malpighi (10 March 1628 – 30 November 1694) was an Italian biologist and physician, who is referred to as the "Founder of microscopical anatomy, histology & Father of physiology and embryology". Malpighi's name is borne by several phy ...


References

Vivian Nutton, "Ancient Medicine" New York: Routledge, 2004.


External links


Ancient Greek Medicine
{{Authority control 4th-century BC Greek physicians Ancient Koans Year of death unknown 340s BC births