The Poxvirus AX element late mRNA family represents a
''cis''-regulatory element present at the 3' end of
poxvirus
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated wit ...
late ATI
mRNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein.
mRNA is created during the ...
and is known as the AX element. The AX element is involved in directing the efficient production and orientation-dependent formation of late
RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...
s.
It is likely that this element directs the endonucleolytic cleavage of the transcript. It has been shown that the F17R late mRNA transcript which is also cleaved is also likely to share a common factor in their mechanism despite a lack of any obvious similarity in its cis-regulatory RNA element.
See also
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Potato virus X cis-acting regulatory element
The Potato virus X cis-acting regulatory element is a cis-acting regulatory element found in the 3' UTR of the Potato virus X genome. This element has been found to be required for minus strand RNA accumulation and is essential for efficient vi ...
References
External links
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Cis-regulatory RNA elements
Poxviruses
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