In humans
The human hepatic portal system delivers about three-fourths of the blood going to the liver. The final common pathway for transport of venous blood from spleen, pancreas, gallbladder and the abdominal portion of the gastrointestinal tract (with the exception of the inferior part of the anal canal and sigmoid colon) is through the '' hepatic portal vein''. This portal vein is formed by the union of the ''superior mesenteric vein'' and the ''splenic vein'' posterior to the neck of the pancreas at the level of vertebral body L1. Ascending towards the liver, the portal vein passes posterior to the superior part of the duodenum and enters the right margin of the lesser omentum. It is anterior to the omental foramen and posterior to both the bile duct, which is slightly to the right, and the hepatic artery proper, which is slightly to the left. On approaching the liver, the portal vein divides into right and left branches which enter the liver parenchyma. It gives off the right and left gastric veins, the cystic vein and the para-umbilical veins as tributaries. The hypophyseal portal system portal venous system transports hormones from the hypothalamus to the pituitary gland. Adrenal medulla capillaries are downstream from adrenal cortex capillaries. This portal system delivers high concentrations of adrenal cortical hormones to the adrenal medulla. In particular, glucocorticoids induce the enzymatic conversion of norepinephrine to epinephrine in the adrenal medulla. By contrast, the ganglia of the sympathetic trunk produce mainly norepinephrine because their cells aren't bathed in high concentrations of glucocorticoids. Renal tubular capillaries are downstream from renal glomerular capillaries. The venous blood of the islets of Langerhans is upstream from the capillary system of the exocrine pancreas via ''vasa efferentia''. The acini of the exocrine pancreas are therefore directly exposed to high concentrations of hormones from the endocrine pancreas, forming the pancreatic portal system.References
{{reflist Angiology