The
enzyme guluronate-specific alginate lyase (, formerly called poly(α-
L-guluronate) lyase)
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the following process:
:Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-α-
L-''erythro''-hex-4-enuronosyl groups at their non-reducing ends and α-
L-uluronate at their reducing end.
This enzyme belongs to the family of
lyase
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...
s, specifically those carbon-oxygen lyases acting on polysaccharides. The
systematic name of this enzyme class is alginate α-
L-guluronate—uronate lyase. Other names in common use include alginase II, guluronate lyase,
L-guluronan lyase,
L-guluronate lyase, poly-α-
L-guluronate lyase, and polyguluronate-specific alginate lyase.
Structural studies
As of late 2007, only one
structure
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ...
has been solved for this class of enzymes, with the
PDB accession code .
References
*
*
EC 4.2.2
Enzymes of known structure
{{4.2-enzyme-stub