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Plithotaxis, from the Greek word "πλήΘος", denotes a crowd, swarm, or throng. In collective cellular migration, plithotaxis is the tendency for each individual cell within a monolayer to migrate along the local orientation of the maximal principal stress, or equivalently, minimal intercellular shear stress.Tambe, D.T., Hardin, C., Angelini, T.E., Rajendran, K., Park, C.Y., Serra-Picamal, X., Zhou, E.H., Zaman, M.H., Butler, J.P., Weitz, D.A., Fredberg JJ, Trepat, X, Collective cell guidance by cooperative intercellular forces. ''Nature Materials'',10(6), 469-475, 2011, .Trepat, X, Fredberg, JJ. Plithotaxis and emergent dynamics in collective cellular migration. ''Trends in Cell Biology'' - 23 July 2011, . Plithotaxis requires force transmission across many cell-cell junctions and therefore is an emergent property of the cell group.
Plithotaxis is found to hold at the level of both a subcellular grid point and an individual cell of a confluent monolayer, and the stresses must be tensile.Patel, N.G., Nguyen, A., Xu, N., Ananthasekar, S., Alvarez, D.F., Stevens, T., Tambe, D.T., Unleashing shear: Role of intercellular traction and cellular moments in collective cell migration. ''Biochemical and Biophysical Research Communications'' - February 2020, .
Plithotaxis, from the Greek word "πλήΘος", denotes a crowd, swarm, or throng. In collective cellular migration, plithotaxis is the tendency for each individual cell within a monolayer to migrate along the local orientation of the maximal principal stress, or equivalently, minimal intercellular shear stress.Tambe, D.T., Hardin, C., Angelini, T.E., Rajendran, K., Park, C.Y., Serra-Picamal, X., Zhou, E.H., Zaman, M.H., Butler, J.P., Weitz, D.A., Fredberg JJ, Trepat, X, Collective cell guidance by cooperative intercellular forces. ''Nature Materials'',10(6), 469-475, 2011, .Trepat, X, Fredberg, JJ. Plithotaxis and emergent dynamics in collective cellular migration. ''Trends in Cell Biology'' - 23 July 2011, . Plithotaxis requires force transmission across many cell-cell junctions and therefore is an emergent property of the cell group.
Plithotaxis is found to hold at the level of both a subcellular grid point and an individual cell of a confluent monolayer, and the stresses must be tensile.Patel, N.G., Nguyen, A., Xu, N., Ananthasekar, S., Alvarez, D.F., Stevens, T., Tambe, D.T., Unleashing shear: Role of intercellular traction and cellular moments in collective cell migration. ''Biochemical and Biophysical Research Communications'' - February 2020, .
See also
*Chemotaxis
Chemotaxis (from '' chemo-'' + ''taxis'') is the movement of an organism or entity in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemica ...
* Durotaxis
* Haptotaxis
* Mechanotaxis
References
Cell biology Physiology Signal transduction Emergence {{biology-stub