The "platelet-rich fibrin matrix" (PRFM) method is a

cosmetic surgery Plastic surgery is a surgical specialty involving the restoration, reconstruction or alteration of the human body. It can be divided into two main categories: reconstructive surgery and cosmetic surgery. Reconstructive surgery includes craniofa ...

procedure involving plasma needling. It is a way of extracting platelets from the patient's own blood and using them as a dermal filler – that is, as a substance injected under the skin of the face to try to fill out wrinkles. PRFM is an outpatient procedures that, , costs about $900 to $1,500 in the U.S. and takes less than half an hour. Blood is drawn from the patient's arm and spun in a centrifuge to separate out the platelets, which are then injected back under the patient's facial skin. It can also be combined in a specific way with other fillers. A procedure using this combination has been marketed as the "Vampire facelift"." PRFM has been available on the U.S. market since 2009. It was developed and is marketed by the Aesthetic Factors corporation. While a platelet extraction centrifuge was cleared by the U.S. Food and Drug Administration (FDA) in 2002 platelets extracted in this centrifuge have not been cleared or approved by the FDA for facial rejuvenation. Nonetheless, Selphyl has been described as a "FDA approved dermal filler" in YouTube videos and trade publications. The

efficacy Efficacy is the ability to perform a task to a satisfactory or expected degree. The word comes from the same roots as ''effectiveness'', and it has often been used synonymously, although in pharmacology a pragmatic clinical trial#Efficacy versu ...

of PRFM is contested. , according to a '' New York Times'' report, it is attested by several plastic surgeons who use it but remains unproven by research. Phil Haeck, the president of the

American Society of Plastic Surgeons The American Society of Plastic Surgeons (ASPS) is the largest plastic surgery specialty organization in the world. Founded in 1931, the society is composed of surgeons certified by the American Board of Plastic Surgery or by the Royal College of ...

, dismissed the procedure as "creepy", "a gimmick" and as "antiquated as bloodletting". It is marketed as Selphyl, TruPRP, Emcyte, Regen, and Pure Spin.

References

{{reflist Plastic surgery