The enzyme phosphatidylinositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) that
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the reaction
:1-phosphatidyl-''myo''-inositol 3,4-bisphosphate + H
2O
1-phosphatidyl-1
D-''myo''-inositol 3-phosphate + phosphate
This enzyme belongs to the family of
hydrolases, specifically those acting on phosphoric
monoester bonds. The
systematic name is 1-phosphatidyl-1
D-''myo''-inositol-3,4-bisphosphate 4-phosphohydrolase. Other names in common use include inositol-3,4-bisphosphate 4-phosphatase,
D-''myo''-inositol-3,4-bisphosphate 4-phosphohydrolase, phosphoinositide 4-phosphatase, inositol polyphosphate 4-phosphatase,
D-''myo''-inositol-3,4-bisphosphate 4-phosphohydrolase, and inositol polyphosphate 4-phosphatase type II. This enzyme participates in
inositol phosphate metabolism
Inositol phosphates are a group of mono- to hexaphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation.
The group comprises:
* inosito ...
and
phosphatidylinositol signaling system.
References
*
*
*
EC 3.1.3
Enzymes of unknown structure
{{3.1-enzyme-stub