Phorbol 12,13-dibutyrate (PDBu) is a
phorbol ester
Phorbol esters are a class of chemical compounds found in a variety of plants, particularly in the families Euphorbiaceae and Thymelaeaceae. Chemically, they are ester derivatives of the tetracyclic diterpenoid phorbol.
Biological activity
Prot ...
which is one of the constituents of
croton oil. As an activator of
protein kinase C, it is a weak tumor promoter compared to
12-''O''-tetradecanoylphorbol-13-acetate.
PDBu is widely used as a chemical reagent because of its
solubility
In chemistry, solubility is the ability of a substance, the solute, to form a solution with another substance, the solvent. Insolubility is the opposite property, the inability of the solute to form such a solution.
The extent of the solub ...
in water and other organic solvents.
References
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Butyrate esters
Diterpenes
Alcohols
Ketones
Carcinogens
Cyclopentenes
Phorbol esters