Phlebitis (or Venitis) is
inflammation
Inflammation (from la, wikt:en:inflammatio#Latin, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or Irritation, irritants, and is a protective response involving im ...
of a
vein
Veins are blood vessels in humans and most other animals that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are the pulmonary and umbilical veins, both of which carry oxygenated b ...
, usually in the
leg
A leg is a weight-bearing and locomotive anatomical structure, usually having a columnar shape. During locomotion, legs function as "extensible struts". The combination of movements at all joints can be modeled as a single, linear element ca ...
s. It most commonly occurs in superficial veins. Phlebitis often occurs in conjunction with
thrombosis
Thrombosis (from Ancient Greek "clotting") is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thro ...
and is then called
thrombophlebitis
Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood clot). When it occurs repeatedly in different locations, it is known as thrombophlebitis migrans ( migratory thrombophlebitis).
Signs and symptoms
The following ...
or superficial thrombophlebitis. Unlike
deep vein thrombosis
Deep vein thrombosis (DVT) is a type of venous thrombosis involving the formation of a blood clot in a deep vein, most commonly in the legs or pelvis. A minority of DVTs occur in the arms. Symptoms can include pain, swelling, redness, and enla ...
, the probability that superficial thrombophlebitis will cause a clot to
break up and be transported in pieces to the lung is very low.
Signs and symptoms
* Localized
redness and swelling
* Pain or burning along the length of the vein
* Vein being hard and cord-like
There is usually a slow onset of a tender red area along the superficial veins on the skin. A long, thin red area may be seen as the inflammation follows a superficial vein. This area may feel hard, warm, and tender. The skin around the vein may be itchy and swollen. The area may begin to throb or burn. Symptoms may be worse when the leg is lowered, especially when first getting out of bed in the morning. A low-grade fever may occur. Sometimes phlebitis may occur where a peripheral intravenous line was started. The surrounding area may be sore and tender along the vein.
Cause
Phlebitis is typically caused by local trauma to a vein, usually from the insertion of an intravenous catheter. However, it can also occur due to a complication of connective tissue disorders such as lupus, or of pancreatic, breast, or ovarian cancers. Phlebitis can also result from certain medications and drugs that irritate the veins, such as
desomorphine
Desomorphine is a semi-synthetic opioid commercialized by Roche, with powerful, fast-acting effects, such as sedation and analgesia. It was first discovered and patented by a German team working for Knoll in 1920 but was not generally recognize ...
.
Superficial phlebitis often presents as an early sign in
thromboangiitis obliterans
Thromboangiitis obliterans, also known as Buerger disease (English ; ) or Winiwarter-Buerger disease, is a recurring progressive inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet. It is strongly a ...
(Buerger's disease), a vasculitis that affects small and medium-sized arteries and veins in distal extremities often associated with cigarette smoking.
Management
Treatment usually consists of
NSAID
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
s, such as
ibuprofen and local compression (e.g., by
compression stockings
Compression stockings (Flight Socks, Support Bandage) are a specialized hosiery designed to help prevent the occurrence of, and guard against further progression of, venous disorders such as edema, phlebitis and thrombosis. Compression stockings ...
or a
compress
compress is a Unix shell compression program based on the LZW compression algorithm. Compared to more modern compression utilities such as gzip and bzip2, compress performs faster and with less memory usage, at the cost of a significantly lo ...
). If the phlebitis is associated with local bacterial infection,
antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention o ...
may be used.
For acute infusion superficial thrombophlebitis, not enough evidence exists as of 2015 to determine treatment.
See also
*
Collapsed vein
Collapsed veins are a common injury that results from repeated use of intravenous injections. They are particularly common where injecting conditions are less than ideal, such as in the context of drug abuse.
Causes
Permanent vein collapse occ ...
References
Further reading
* Intravenous Infusion Therapy for Nurses (Second Edition) by Dianne L. Josephson ()
* John Hunter, "Observations on the Inflammation of the Internal Coats of Veins," Transactions of a Society for the Improvement of Medical and Chirurgical Knowledge, vol. 1 (London: 1793) pp. 18–29
External links
eMedicine Health: Phlebitis
{{Authority control
Inflammations
Vascular diseases
pt:Flebite