Phillips Wesley Robbins is a

professor emeritus ''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title ...

in the department of molecular and cell biology at the

Boston University Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original campu ...

School of Dental Medicine. He moved to BU in 1998 following a career of almost 40 years on the faculty at the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...

Early life and education

Robbins was born in 1930 in Barre, Massachusetts and attended high school in West Springfield, Massachusetts. He later described a high school physics course as an inspiration for his plans for a science career, though he continued to consider following the family tradition by becoming a medical

missionary A missionary is a member of a Religious denomination, religious group which is sent into an area in order to promote its faith or provide services to people, such as education, literacy, social justice, health care, and economic development.Tho ...

. He settled on

biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

as his chosen field as an undergraduate at

DePauw University DePauw University is a private liberal arts university in Greencastle, Indiana. It has an enrollment of 1,972 students. The school has a Methodist heritage and was originally known as Indiana Asbury University. DePauw is a member of both the G ...

, from which he graduated in 1952. He received his Ph.D. in 1955 from the

University of Illinois The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the University ...

under the supervision of Herbert E. Carter and then became a

postdoctoral fellow A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...

with

Fritz Lipmann Fritz Albert Lipmann (; June 12, 1899 – July 24, 1986) was a German-American biochemist and a co-discoverer in 1945 of coenzyme A. For this, together with other research on coenzyme A, he was awarded the Nobel Prize in Physiology or Medicine in ...

, first at

Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...

and then moving with the group to

Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...

Academic career

Robbins joined the faculty at the

in 1960 as one of several young biochemists hired by Jack Buchanan into the department of biology. There he worked particularly closely with Salvador Luria, studying the structure and biochemistry of

lipopolysaccharide Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide that are bacterial toxins. They are composed of an O-antigen, an outer core, and an inner core all joined by a covalent bond, and are found in the outer m ...

s. In 1998, after nearly 40 years at MIT, Robbins moved to the

School of Dental Medicine, where he has worked in collaboration with

John Samuelson John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second E ...

and with two of his own former postdoctoral fellows, department head Carlos Hirschberg and associate dean Maria Kukuruzinska. Robbins received the

Eli Lilly Award in Biological Chemistry The Eli Lilly Award in Biological Chemistry was established in 1934. Consisting of a bronze medal and honorarium, its purpose is to stimulate fundamental research in biological chemistry by scientists not over thirty-eight years of age. The Award i ...

in 1966, was elected to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

in 1982 and received the Karl Meyer Award for Lifetime Achievement in Glycobiology in 2000.

Research

Robbins' research has focused on a variety of biochemical pathways. In his early career at MIT, he worked closely with Luria studying the structure and biosynthesis of

s, including elucidating the structure of

bactoprenol Bactoprenol also known as dolichol-11 and (isomerically vaguely) C55-isoprenyl alcohol (C55-OH) is a lipid first identified in certain species of lactobacili. It is a hydrophobic alcohol that plays a key role in the growth of cell walls (peptido ...

and identifying the direction of chain elongation in LPS synthesis in bacteria. He later moved on to studying the biochemistry of the

eukaryotic Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacte ...

N-linked glycosylation ''N''-linked glycosylation, is the attachment of an oligosaccharide, a carbohydrate consisting of several sugar molecules, sometimes also referred to as glycan, to a nitrogen atom (the amide nitrogen of an asparagine (Asn) residue of a protein), ...

pathway and more recently, with

, has studied the evolution of this pathway in

protist A protist () is any eukaryotic organism (that is, an organism whose cells contain a cell nucleus) that is not an animal, plant, or fungus. While it is likely that protists share a common ancestor (the last eukaryotic common ancestor), the exc ...

s. He has also worked on the problem of

chitin Chitin ( C8 H13 O5 N)n ( ) is a long-chain polymer of ''N''-acetylglucosamine, an amide derivative of glucose. Chitin is probably the second most abundant polysaccharide in nature (behind only cellulose); an estimated 1 billion tons of chit ...

synthesis and its role in

yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitut ...

References

{{DEFAULTSORT:Robbins, Phillips 1930 births Living people Boston University faculty American biochemists Members of the National Academy of Medicine