Pheophorbide a oxygenase (, ''pheide a monooxygenase'', ''pheide a oxygenase'', ''PAO'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name ''pheophorbide-a,NADPH:oxygen oxidoreductase (biladiene-forming)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:
Pheophorbide a
Pheophorbide or phaeophorbide is a product of chlorophyll breakdown and a derivative of pheophytin where both the central magnesium has been removed and the phytol tail has been hydrolyzed. It is used as a photosensitizer
Photosensitizers produ ...
+ NADPH + H
+ + O
2 red chlorophyll catabolite + NADP
+
Pheophorbide a oxygenase participates in
chlorophyll
Chlorophyll (also chlorophyl) is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words , ("pale green") and , ("leaf"). Chlorophyll allow plants to a ...
degradation. Loss-of-function mutations in the gene can lead to a ''stay-green'' phenotype in plants.
References
External links
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EC 1.14.15