Anilides (or phenylamides) are a class of chemical compounds, which are
amide
In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula , where R, R', and R″ represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it i ...
derivatives of
aniline
Aniline is an organic compound with the formula C6 H5 NH2. Consisting of a phenyl group attached to an amino group, aniline is the simplest aromatic amine. It is an industrially significant commodity chemical, as well as a versatile starti ...
.
Preparation
Aniline reacts with
acyl chlorides or
carboxylic anhydride
An organic acid anhydride is an acid anhydride that is an organic compound. An acid anhydride is a compound that has two acyl groups bonded to the same oxygen atom. A common type of organic acid anhydride is a carboxylic anhydride, where the pa ...
s to give anilides. For example, reaction of aniline with
acetyl chloride
Acetyl chloride (CH3COCl) is an acyl chloride derived from acetic acid. It belongs to the class of organic compounds called acid halides. It is a colorless, corrosive, volatile liquid. Its formula is commonly abbreviated to AcCl.
Synthesis
On a ...
provides
acetanilide
Acetanilide is an odourless solid chemical of leaf or flake-like appearance. It is also known as ''N''-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin.
Preparation and properties
Acetanilide can be ...
(CH
3-CO-NH-C
6H
5). At high temperatures, aniline and carboxylic acids react to give anilides.
Uses
*
Herbicides
*
Fungicides
Fungicides are biocidal chemical compounds or biological organisms used to kill parasitic fungi or their spores. A fungistatic inhibits their growth. Fungi can cause serious damage in agriculture, resulting in critical losses of yield, quality ...
-
Oxycarboxin
Oxycarboxin is an organic compound used as a fungicide. It is an anilide.
Uses
Oxycarboxin is used to control rust diseases (e.g. soybean rust).
History
Oxycarboxin has been commercially available since 1966.
Preparation
Oxycarboxin is prepared ...
,