Phenindione is an
anticoagulant which functions as a
Vitamin K antagonist
Vitamin K antagonists (VKA) are a group of substances that reduce blood clotting by reducing the action of vitamin K. The term "vitamin K antagonist" is technically a misnomer, as the drugs do not directly antagonise the action of vitamin K in t ...
.
Phenindione was introduced in the early 1950s. It acts similar to
warfarin
Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner). It is commonly used to prevent blood clots such as deep vein thrombosis and pulmonary embolism, and to prevent st ...
, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred.
References
External links
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Vitamin K antagonists
Indandiones
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