Peter J. H. Scott FRSC CChem (born July 27, 1979) is a British and American chemist and radiochemist who is an Associate Professor of Radiology and Pharmacology, as well as a Faculty Scientist in the Interdepartmental Program in Medicinal Chemistry and a Core Member of the Rogel Cancer Center at the

University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...

in the United States. He is Chief of Nuclear Medicine and Director of the University of Michigan Positron Emission Tomography (

PET A pet, or companion animal, is an animal kept primarily for a person's company or entertainment rather than as a working animal, livestock, or a laboratory animal. Popular pets are often considered to have attractive appearances, intelligence, ...

) Center, and runs a research group developing new

radiochemistry Radiochemistry is the chemistry of radioactive materials, where radioactive isotopes of elements are used to study the properties and chemical reactions of non-radioactive isotopes (often within radiochemistry the absence of radioactivity leads to ...

methodology and novel PET

radiotracers A radioactive tracer, radiotracer, or radioactive label is a chemical compound in which one or more atoms have been replaced by a radionuclide so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tr ...

Life

Peter Scott was born and grew up in North East England and attended

Whitley Bay High School Whitley Bay High School is a coeducational upper school and sixth form located in Whitley Bay, North Tyneside, England. Location It is situated next to ''Monkseaton Drive'' (A1148), towards the north of Monkseaton, and is less than a mile from ...

. He received his undergraduate degree with first class honors in medicinal and pharmaceutical chemistry from

Loughborough University Loughborough University (abbreviated as ''Lough'' or ''Lboro'' for post-nominals) is a public research university in the market town of Loughborough, Leicestershire, England. It has been a university since 1966, but it dates back to 1909, when L ...

in 2001, after conducting research with Raymond Jones. He subsequently obtained his PhD in organic chemistry from

Durham University , mottoeng = Her foundations are upon the holy hills (Psalm 87:1) , established = (university status) , type = Public , academic_staff = 1,830 (2020) , administrative_staff = 2,640 (2018/19) , chancellor = Sir Thomas Allen , vice_chan ...

in 2005, where he was a member of

Ustinov College Ustinov College is the largest college of Durham University, located in Durham, North East England. Founded as the Graduate Society in 1965, it became a college in 2003 and was named after then-chancellor, Sir Peter Ustinov. Formerly at the Howl ...

, under the mentorship of Patrick G. Steel. Scott then moved to the United States to undertake postdoctoral research in organometallic chemistry at

SUNY Buffalo The State University of New York at Buffalo, commonly called the University at Buffalo (UB) and sometimes called SUNY Buffalo, is a public research university with campuses in Buffalo and Amherst, New York. The university was founded in 1846 ...

under Huw Davies, and PET radiochemistry at the University of Michigan with Michael Kilbourn.

Research

Scott runs a research group developing new metal-catalyzed methods for incorporating

fluorine-18 Fluorine-18 (18F) is a fluorine radioisotope which is an important source of positrons. It has a mass of 18.0009380(6) u and its half-life is 109.771(20) minutes. It decays by positron emission 96% of the time and electron capture 4% of the time ...

and

carbon-11 Carbon (6C) has 15 known isotopes, from to , of which and are stable. The longest-lived radioisotope is , with a half-life of years. This is also the only carbon radioisotope found in nature—trace quantities are formed cosmogenically by ...

into bioactive molecules as well as novel PET

for imaging

neurodegenerative disorders A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic ...

. His methodology work aims to improve the synthesis of PET radiotracers and he has an active collaboration with Prof. Melanie Sanford's group that is funded by NIBIB. Together they have developed methods for the Cu-mediated radiofluorination and radiocyanation of (mesityl)(aryl)iodonium salts, boronic acids and stannanes, as well as new methods for radiofluorination of C-H bonds and aryl halides. Scott has also introduced methods for green radiochemistry, for which he received the Michigan

Green Chemistry Green chemistry, also called sustainable chemistry, is an area of chemistry and chemical engineering focused on the design of products and processes that minimize or eliminate the use and generation of hazardous substances. While environmental che ...

Governor's Award in 2014. In 2019, Prof. Scott was elected as a Fellow of the

Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Ro ...

( FRSC), and received a Distinguished Investigator Award from the Academy for Radiology & Biomedical Imaging Research. In 2021, he was recognized as a Fellow of the

Society of Nuclear Medicine and Molecular Imaging The Society of Nuclear Medicine and Molecular Imaging (SNMMI), formerly the Society of Nuclear Medicine, is a nonprofit scientific and professional organization that promotes the science, technology and practical application of nuclear medicine a ...

Bibliography

1. Linker Strategies in Solid-phase Organic Synthesis (Editor, 2009)
2. Solid-Phase Organic Syntheses, Volume 2: Solid-Phase Palladium Chemistry (Wiley Series on Solid-Phase Organic Syntheses) (Editor, 2012)
3. Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (Editor, 2012)
4. Radiochemical Syntheses: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Volume 2 (Editor, 2015)
5. Handbook of Radiopharmaceuticals (2nd Edition): Methodology and Applications (Editor, 2021)
6. Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals (co-authored with

International Atomic Energy Agency The International Atomic Energy Agency (IAEA) is an intergovernmental organization that seeks to promote the peaceful use of nuclear energy and to inhibit its use for any military purpose, including nuclear weapons. It was established in 1957 ...

, 2021) Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals; https://www.iaea.org/publications/14925/production-and-quality-control-of-fluorine-18-labelled-radiopharmaceuticals

References

{{DEFAULTSORT:Scott, Peter J. H. 1979 births Living people 21st-century British chemists British expatriate academics in the United States Alumni of Loughborough University University of Michigan faculty Radiochemistry Alumni of Ustinov College, Durham