Pelvic Lipomatosis
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Pelvic lipomatosis is a
rare disease A rare disease is any disease that affects a small percentage of the population. In some parts of the world, an orphan disease is a rare disease whose rarity means there is a lack of a market large enough to gain support and resources for discove ...
that is most often seen in older
obese Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's we ...
black men with
hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high bl ...
. In pelvic
lipomatosis Lipomatosis is believed to be an autosomal dominant condition in which multiple lipomas are present on the body. Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. In 1993, a gene ...
, abnormally dense deposits of otherwise apparently normal
fat In nutrition science, nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such chemical compound, compounds, most commonly those that occur in living beings or in food. The term often refers spec ...
may be observed in the spaces of the pelvic area. Associated with
cystitis glandularis Cystitis glandularis is the transformation of mucosal cells lining the urinary bladder. They undergo glandular metaplasia, a process in which irritated tissues take on a different form, in this case that of a gland. The main importance is in the ...
, a precursor to
adenocarcinoma Adenocarcinoma (; plural adenocarcinomas or adenocarcinomata ) (AC) is a type of cancerous tumor that can occur in several parts of the body. It is defined as neoplasia of epithelial tissue that has glandular origin, glandular characteristics, or ...
of the
urinary bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters ...
. It is associated with deposition of mature unencapsulated fat in the retroperitoneal pelvic space producing the typical "pear-shaped" appearance of the bladder on CT scan. This condition also causes a straightening and tubular appearance of the rectum.


References


Further reading

* Fogg LB, Smyth JW. ''Pelvic lipomatosis: a condition simulating pelvic neoplasm.'' Radiology. 1968;90:558.


External links

* http://www.medscape.com/viewarticle/417016_print
An aggressive pelvic lipomatosis
Medical conditions related to obesity {{endocrine-disease-stub