Pauls Stradiņš
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Pauls Stradiņš (17 January 1896 – 14 August 1958) was a
Latvia Latvia ( or ; lv, Latvija ; ltg, Latveja; liv, Leţmō), officially the Republic of Latvia ( lv, Latvijas Republika, links=no, ltg, Latvejas Republika, links=no, liv, Leţmō Vabāmō, links=no), is a country in the Baltic region of ...
n professor,
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
, and
surgeon In modern medicine, a surgeon is a medical professional who performs surgery. Although there are different traditions in different times and places, a modern surgeon usually is also a licensed physician or received the same medical training as ...
who founded the Museum of the History of Medicine in
Riga Riga (; lv, Rīga , liv, Rīgõ) is the capital and largest city of Latvia and is home to 605,802 inhabitants which is a third of Latvia's population. The city lies on the Gulf of Riga at the mouth of the Daugava river where it meets the Ba ...
.


Early life

Stradiņš was born in Eķengrāve (german: Eckengraf) (now Viesīte,
Jēkabpils Municipality Jēkabpils Municipality ( lv, Jēkabpils novads) is a municipality in Latvia. The municipality was formed in 2009 by merging Ābeļi Parish, Dignāja Parish, Dunava Parish, Kalna Parish, Leimaņi Parish, Rubene Parish and Zasa Parish. Dur ...
) as the son of a craftsman and pub owner. He graduated from the Riga Alexander Gymnasium in 1914 and entered the
S. M. Kirov Military Medical Academy The S. M. Kirov Military Medical Academy (russian: Военно-медицинская академия имени С. М. Кирова) is a higher education institution of military medicine in Saint Petersburg and the Russian Federation. Senior ...
in Petrograd (now
Saint Petersburg Saint Petersburg ( rus, links=no, Санкт-Петербург, a=Ru-Sankt Peterburg Leningrad Petrograd Piter.ogg, r=Sankt-Peterburg, p=ˈsankt pʲɪtʲɪrˈburk), formerly known as Petrograd (1914–1924) and later Leningrad (1924–1991), i ...
), where his professors included the
Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ...
-winning physiologist
Ivan Pavlov Ivan Petrovich Pavlov ( rus, Ива́н Петро́вич Па́влов, , p=ɪˈvan pʲɪˈtrovʲɪtɕ ˈpavləf, a=Ru-Ivan_Petrovich_Pavlov.ogg; 27 February 1936), was a Russian and Soviet experimental neurologist, psychologist and physiol ...
.


Medical education

During
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
, Stradiņš was an army doctor on the Russian Western Front and in
Persia Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkmeni ...
, and then the chief of a surgical department in
Vladivostok Vladivostok ( rus, Владивосто́к, a=Владивосток.ogg, p=vɫədʲɪvɐˈstok) is the largest city and the administrative center of Primorsky Krai, Russia. The city is located around the Zolotoy Rog, Golden Horn Bay on the Sea ...
. After graduating from the military medical academy in 1919, he became an institute doctor (i.e., a candidate for an M.D. degree) in the academy's hospital surgery clinic, headed by Professor Sergey Fedorov, the former private surgeon of Tsar
Nicholas II Nicholas II or Nikolai II Alexandrovich Romanov; spelled in pre-revolutionary script. ( 186817 July 1918), known in the Russian Orthodox Church as Saint Nicholas the Passion-Bearer,. was the last Emperor of Russia, King of Congress Pola ...
. Under Fedorov's supervision, Stradiņš completed a
doctoral thesis A thesis ( : theses), or dissertation (abbreviated diss.), is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings.International Standard ISO 7144: ...
on the treatment of
peripheral nerve injury Nerve injury is an injury to nervous tissue. There is no single classification system that can describe all the many variations of nerve injuries. In 1941, Seddon introduced a classification of nerve injuries based on three main types of nerve f ...
. It included data from 862 patients on trophic, secretory and
vasomotor Vasomotor refers to actions upon a blood vessel which alter its diameter. More specifically, it can refer to vasodilator action and vasoconstrictor action. Control Sympathetic innervation Sympathetic nerve fibers travel around the tunica media of ...
disturbances after injuries to the extremities, and on surgical and nonsurgical treatment methods. In 1919, Stradiņš, working with N. N. Yelanski, I. R. Petrov, and other colleagues, produced the first standard serum for
blood transfusion Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but mo ...
in
Soviet Russia The Russian Soviet Federative Socialist Republic, Russian SFSR or RSFSR ( rus, Российская Советская Федеративная Социалистическая Республика, Rossíyskaya Sovétskaya Federatívnaya Soci ...
. Three years later, he ran an experiment on himself: A periarterial
sympathectomy A sympathectomy is an irreversible procedure during which at least one sympathetic ganglion is removed. One example is the lumbar sympathectomy, which is advised for occlusive arterial disease in which L2 and L3 ganglia along with intervening sym ...
(pioneered by Mathieu Jaboulay) was performed on his left shoulder by V. N. Shamov, and Stradiņš personally evaluated the results. He also carried out physiological and
pharmacological Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemica ...
experiments in the laboratories of the physiologist Ivan Pavlov and pharmacologist
Nikolai Kravkov Nikolai Pavlovich Kravkov (in Russian Николай Павлович Кравков) was a prominent Russian pharmacologist, Full Member of the Imperial Military Medical Academy (1914), Corresponding Member of the Russian Academy of Science (192 ...
. Fedorov regarded Stradiņš as one of his "best and most gifted pupils, and his works on the spontaneous gangrene and operations on nerves as indubitably excellent".


Career


Pre-World War II

Stradiņš returned to Riga at the end of 1923 and joined the faculty of medicine at the newly founded
University of Latvia University of Latvia ( lv, Latvijas Universitāte, shortened ''LU'') is a state-run university located in Riga, Latvia established in 1919. The ''QS World University Rankings'' places the university between 801st and 1000th globally, seventh ...
. In 1924, he became the first
Rockefeller Fellow The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carneg ...
from Latvia. During his fellowship, he worked under
Alfred Washington Adson Alfred Washington Adson (March 13, 1887 – November 12, 1951) was an American physician, military officer, and surgeon. He was in medical practice with the Mayo Clinic and the Mayo Graduate School of Medicine of the University of Minnesota at ...
at the
Mayo Clinic The Mayo Clinic () is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, ...
in
Rochester, Minnesota Rochester is a city in the U.S. state of Minnesota and the county seat of Olmsted County. Located on rolling bluffs on the Zumbro River's south fork in Southeast Minnesota, the city is the home and birthplace of the renowned Mayo Clinic. Acco ...
, as well as under C. C. Choyce at
Imperial College London Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cu ...
. In 1927, he defended his second doctoral thesis at the University of Latvia, summarizing the results of his research in Petrograd, Rochester, and Riga on the genesis and treatment of obliterating endarteritis. The main results were published in German and Russian medical journals and were recognized by the Latvian Cultural Foundation in 1928. At the end of the 1920s, Stradiņš turned his attention from peripheral neurosurgery to
abdominal surgery The term abdominal surgery broadly covers Surgery, surgical procedures that involve opening the abdomen (laparotomy). Surgery of each abdominal organ is dealt with separately in connection with the description of that organ (see stomach, kidney, l ...
and
cancer treatment Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. ...
. In 1931, he was appointed medical director of the 2nd City Hospital of Riga (now
Pauls Stradiņš Clinical University Hospital Pauls Stradiņš Clinical University Hospital ( lv, Paula Stradiņa Klīniskā universitātes slimnīca) is an outpatient and hospital health care service provider in Riga, Latvia. This hospital also plays a role in medical science and medical ...
), which he helped to modernize. In 1933, he became a professor of surgery, a position he held until his death in 1958. From 1927–39, he interacted with research centers all over Europe and adopted foreign innovations in Latvia. He became the country's leading
oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ó ...
specialist, and in 1935, he founded the first surgical department for cancer treatment at his hospital. In 1938, he founded a specialized cancer hospital in Riga. He paid primary attention to the treatment of inoperable cancer patients, contacted experts from Germany and Austria, and presented his preliminary results on the topic at the 1st Conference of Medical Doctors of the Baltic Countries and Finland, held in 1938 in
Helsinki Helsinki ( or ; ; sv, Helsingfors, ) is the Capital city, capital, primate city, primate, and List of cities and towns in Finland, most populous city of Finland. Located on the shore of the Gulf of Finland, it is the seat of the region of U ...
. Stradiņš was one of the most recognized doctors in Latvia because of his successful private practice and his organizational activities in health care. In 1937, during the authoritarian regime of
Kārlis Ulmanis Kārlis Augusts Vilhelms Ulmanis (; 4 September 1877 – 20 September 1942) was a Latvian politician. He was one of the most prominent Latvian politicians of pre-World War II Latvia during the Interwar period of independence from November 1918 to ...
, he founded and chaired the Society for Health Promotion ( Latvian: ''Veselības veicināšanas biedrība''). The society—which included anti-cancer, anti-
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
, and
venereology Venereology is a branch of medicine that is concerned with the study and treatment of sexually transmitted diseases (STDs). The name derives from Roman goddess Venus, associated with love, beauty and fertility. A physician specializing in vener ...
sections—maintained
sanatorium A sanatorium (from Latin '' sānāre'' 'to heal, make healthy'), also sanitarium or sanitorium, are antiquated names for specialised hospitals, for the treatment of specific diseases, related ailments and convalescence. Sanatoriums are often ...
s and organized exhibitions on health care and demography. It also included the Institute of Research of the Nation’s Life Resources (Latvian: ''Tautas dzīvā spēka pētīšanas institūts''), headed by Jacob Prīmanis, which was responsible for demographic, genealogical, and eugenics research on the population of Latvia. Stradiņš was a co-founding member and representative of Latvia at the International Academy for Improvement of Medical Education, founded in
Budapest Budapest (, ; ) is the capital and most populous city of Hungary. It is the ninth-largest city in the European Union by population within city limits and the second-largest city on the Danube river; the city has an estimated population ...
in 1938, and served as the Latvian delegate to several international health organizations. All these activities ceased when the Soviet Union annexed Latvia in 1940. During the first year of the Soviet occupation, Stradiņš retained his hospital duties and renewed contacts with his former colleagues in Soviet Russia. But with the entrance of Nazi forces in 1941, he was arrested because of his humanitarian aid to Jews and wounded soldiers at his hospital. After his release, he was dismissed from his job, and later also from the cancer hospital, where he had tried to save mentally disabled patients.


Post-World War II

In contrast to the majority of Latvian medical professors and doctors, Stradiņš did not escape to the West during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
. He was one of the few non-Communist Latvian intellectuals who stayed for patriotic reasons and tried to take positive action under the new conditions, and he thus became a key figure not only in medicine, but also in public activities. Stradiņš served as dean of his hospital's faculty of medicine from 1944–46, as the chief doctor of the clinical hospital from 1944–47, as chairman of the Medicine Science Council at the Health Ministry from 1945–48, and as the chief surgeon and chief oncologist of the
Latvian Soviet Socialist Republic The Latvian Soviet Socialist Republic (Latvian SSR), also known as Soviet Latvia or simply Latvia, was a federated republic within the Soviet Union, and formally one of its 16 (later 15) constituent republics. The Latvian Soviet Socialist Rep ...
. He was elected to the
USSR Academy of Medical Sciences The USSR Academy of Medical Sciences (russian: Акаде́мия медици́нских нау́к СССР) was the highest scientific and medical organization founded in the Soviet Union founded in 1944. Its successor is the Russian Academy of ...
in 1945 and nominated as one of the first full members of the newly founded
Latvian Academy of Sciences The Latvian Academy of Sciences ( lv, Latvijas Zinātņu akadēmija) is the official Academy of Sciences, science academy of Latvia and is an association of the country's foremost scientists. The academy was founded as the ''Latvian SSR Academy o ...
in 1946. Nevertheless, under the ideological repression of the immediate postwar period—driven by
Stalinism Stalinism is the means of governing and Marxist-Leninist policies implemented in the Soviet Union from 1927 to 1953 by Joseph Stalin. It included the creation of a one-party totalitarian police state, rapid industrialization, the theory ...
and the Soviet Union's struggle against Western influences—Stradiņš soon lost his positions in medicine and science. He was dismissed from his main duties and became a victim of ideological campaigns from 1947–49. However, he was allowed to continue working as a professor, and until 1950, he held the position of director of the Institute of Experimental Medicine at the Latvian Academy of Sciences. During the 1940s and 1950s, he conducted research on cancer and was the first to use the
nitrofuran Nitrofurans are a class of drugs typically used as antibiotics or antimicrobials. The defining structural component is a furan ring with a nitro group. Drugs Members of this class of drugs include: * Antibacterials (antibiotics) ** Difurazone ...
agent Furacilin and
thiotepa Thiotepa (INN), sold under the brand name Tepadina, is a medication used to treat cancer. Thiotepa is an organophosphorus compound with the formula (C2H4N)3PS. It is an analog of ''N'',''N′'',''N′′''-triethylenephosphoramide ( ...
as
chemotherapy Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherap ...
in the Soviet Union. He also helped educate a generation of Latvian physicians and surgeons, and founded a museum on the
history of medicine The history of medicine is both a study of medicine throughout history as well as a multidisciplinary field of study that seeks to explore and understand medical practices, both past and present, throughout human societies. More than just histo ...
. The museum grew out of Stradiņš' private collection, which he began in prewar Latvia. In the 1930s, the collection was on the premises of his clinical hospital. He completed it and donated it to the state in 1957. It was the biggest collection on the history of world medicine in the Soviet Union, and in 1958, it was named after Stradiņš. In the last years of his life, after
Joseph Stalin Joseph Vissarionovich Stalin (born Ioseb Besarionis dze Jughashvili; – 5 March 1953) was a Georgian revolutionary and Soviet political leader who led the Soviet Union from 1924 until his death in 1953. He held power as General Secreta ...
’s death, Stradiņš was " rehabilitated" from various charges. From 1955–58, he served as a deputy on the Supreme Soviet of the Latvian SSR, the legislature of Soviet Latvia. In his last months, he organized the first cardiothoracic operations and arranged for official recognition of his museum. He died on 14 August 1958, a year and a half after having a
stroke A stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functionin ...
.


Legacy

Stradiņš' name is borne by his museum— Pauls Stradiņš Museum for the History of Medicine —as well as by several other institutions, including the Pauls Stradiņš Clinical University Hospital (since 1958) and the P. Stradiņš Health and Social Care College in
Jūrmala Jūrmala (; "seaside") is a state city in Latvia, about west of Riga. Jūrmala is a resort town stretching and sandwiched between the Gulf of Riga and the Lielupe River. It has a stretch of white-sand beach, and a population of 49,325 in 2019 ...
(since 1989). In 1998, the Riga Medical Institute was reorganized and renamed
Riga Stradiņš University Riga Stradiņš University (RSU) ( lv, Rīgas Stradiņa universitāte, la, Universitas Rigensis Stradina) is a public university located in the city of Riga, Latvia. The Stradiņš (pronounced stradiɲʃ name in the university's title is owed ...
. The name was affirmed by Latvia's Parliament, the
Saeima The Saeima () is the parliament of the Latvia, Republic of Latvia. It is a unicameral parliament consisting of 100 members who are elected by proportional representation, with seats allocated to political parties which gain at least 5% of the po ...
, in 2002. Stradiņš was a many-sided physician, active in surgery, oncology, physiotherapy, pharmacology, blood transfusion,
urology Urology (from Greek οὖρον ''ouron'' "urine" and '' -logia'' "study of"), also known as genitourinary surgery, is the branch of medicine that focuses on surgical and medical diseases of the urinary-tract system and the reproductive org ...
, and
dieting Dieting is the practice of eating food in a regulated way to decrease, maintain, or increase body weight, or to prevent and treat diseases such as diabetes and obesity. As weight loss depends on calorie intake, different kinds of calorie-redu ...
, as well as health care administration. He introduced many modern diagnostic and treatment practices to Latvia and investigated new methods for the early detection of cancer. He was also a member of the editorial boards of three leading Soviet medical journals: ''Klinitcheskaya Medicina'', ''Eksperimental'naya Chirurgija'', and ''Voprosy onkologiji''. He published about 80 scientific papers in Russian, German, Latvian, Polish, Finnish, Lithuanian, and English, and a three-volume, Russian-language edition of his selected works was issued posthumously from 1963–65. He received the Latvian "Croix de la Reconnaissance" in 1938, and the Soviet
Order of the Red Banner of Labor The Order of the Red Banner of Labour (russian: Орден Трудового Красного Знамени, translit=Orden Trudovogo Krasnogo Znameni) was an order of the Soviet Union established to honour great deeds and services to th ...
in 1956. He was a Merited Scientist of the Latvian SSR (1945) and an honorary member (1957) of the N. Pirogov Society, the oldest Russian association for surgeons. The Pauls Stradiņš Award—established in 1983 to honor merits in the history of medicine, and in 1991 to honor merits in medical practice—is Latvia's most prestigious award in the medical sciences.


Family and colleagues

Stradiņš' wife, Ņina Stradiņa (née Malysheva, 1897–1991), was one of the pioneers of physiotherapeutic treatment in Latvia. They had four children: * Irēna Stradiņa (1925–1972), a painter and architect * Maija Sosāre (1926–2008), an English philologist and head of the foreign languages department at the Riga Medical Institute * Jānis Stradiņš (1933–2019), a chemist, science historian, and former president of the Latvian Academy of Sciences * Asja Eglīte (b. 1943), a physician and physiotherapist at Pauls Stradiņš Clinical University Hospital His grandchildren are: *
Pauls Stradiņš Jr Pauls Stradiņš Jr. (born 1963) is a physicist at the National Renewable Energy Laboratory in Golden, Colorado, and a foreign member of the Latvian Academy of Sciences. Currently he is the principal scientist and a project leader of the silico ...
. (b. 1963), a physicist at the
National Renewable Energy Laboratory The National Renewable Energy Laboratory (NREL) in the US specializes in the research and development of renewable energy, energy efficiency, energy systems integration, and sustainable transportation. NREL is a federally funded research and d ...
in
Golden, Colorado Golden is a List of municipalities in Colorado#Home rule municipality, home rule city that is the county seat of Jefferson County, Colorado, Jefferson County, Colorado, United States. The city population was 20,399 at the 2020 United States Censu ...
, and a foreign member of the Latvian Academy of Sciences * Pēteris Stradiņš (b. 1971), a cardiac surgeon, associate professor at Riga Stradiņš University, head of cardiac surgery at Pauls Stradiņš Clinical University Hospital, and corresponding member of the Latvian Academy of Sciences * Andrejs Ērglis (b. 1965), a cardiologist, professor and head of Cardiology and Cardiac Surgery Department at the University of Latvia, and vice president of the Latvian Academy of Sciences * Linda Sosāre (b. 1963), a gastroenterologist and former head of the endoscopy department at Pauls Stradiņš Clinical University Hospital * Māra Sosāre (b. 1957), an English philologist * Adrienna Kalniņa (b. 1953), widow of the cardiologist Uldis Kalniņš Among his closest associates and colleagues were Ēvalds Ezerietis, Vladimirs Utkins, Jānis Slaidiņš, Veronika Rozenbaha, Jevgēnijs Linārs, Lazar Yavorkovski, Ksenija Skulme, Ojārs Aleksis, Eduards Smiltēns, Izidors Sjakste, Velta Bramberga, Rasma Ceplīte, Guntis Vitenbergs, Anna Bormane, Kārlis Dolietis, Mihails Dubinskis, Arturs Rocēns, Valdis Kraulis, Pāvils Purviņš, Vilhelms Pampe, Jānis Erdmanis, and Aleksandrs Marovskis.


Notes

* Akadēmiķis Pauls Stradiņš. Bibliogrāfija. Rīga, 1959 (in Latvian, Russian) * Professors Pauls Stradiņš dzīvē un darbā. Rīga, 1961 (in Latvian) * A. Vīksna. Paula Stradiņa dzīves un darbības vietas. Rīga, 1973 (in Latvian), 1978 (Russian translation) * J. Stradiņš, K. Ē. Ārons, A. Vīksna. Tāds bija mūsu laiks. Veltījums P. Stradiņa 100gadei. Rīga, 1996. 491 p. (in Latvian) * J. Stradiņš, J. Salaks. (Edit.) Materials about Pauls Stradins and his museum. Acta Medico-Historica Rigensia. Vol. VIII. Rīga, 2007. 430 p. (in Latvian, Russian, English) * Страдынь П. И. Избранные труды. Рига, т. 1-3, 1963—1965 (Selected works, in Russian) * Павел Иванович Страдынь — врач, ученый, человек. Отв. ред. В. В. Канеп. Рига: Зинатне, 1967. 392 с. (in Russian)


References


External links

* {{DEFAULTSORT:Stradins, Pauls 1896 births 1958 deaths People from Jēkabpils Municipality People from Courland Governorate Members of the Supreme Soviet of the Latvian Soviet Socialist Republic, 1955–1959 Latvian surgeons 20th-century surgeons Physicians from the Russian Empire Expatriates from the Russian Empire in Iran Soviet surgeons S.M. Kirov Military Medical Academy alumni Academic staff of the University of Latvia Academic staff of Riga Stradiņš University Corresponding Members of the USSR Academy of Medical Sciences Academicians of the Latvian SSR Academy of Sciences Russian military personnel of World War I Recipients of the Order of the Red Banner of Labour Deaths from cerebrovascular disease