The partial specific volume

\bar,

express the variation of the extensive volume of a mixture in respect to composition of the masses. It is the

partial derivative In mathematics, a partial derivative of a function of several variables is its derivative with respect to one of those variables, with the others held constant (as opposed to the total derivative, in which all variables are allowed to vary). P ...

of volume with respect to the mass of the component of interest. :

V=\sum _^n m_i \bar,

where

\bar

is the partial specific volume of a component

i

defined as: :

\bar=\left( \frac \right)_.

The PSV is usually measured in milliLiters (mL) per

gram The gram (originally gramme; SI unit symbol g) is a Physical unit, unit of mass in the International System of Units (SI) equal to one thousandth of a kilogram. Originally defined in 1795 as "the absolute Mass versus weight, weight of a volume ...

(g), proteins > 30 kDa can be assumed to have a partial specific volume of 0.708 mL/g. Experimental determination is possible by measuring the natural frequency of a U-shaped tube filled successively with air, buffer and protein solution.

Properties

The weighted sum of partial specific volumes of a mixture or solution is an inverse of density of the mixture namely the

specific volume In thermodynamics, the specific volume of a substance (symbol: , nu) is the quotient of the substance's volume () to its mass (): :\nu = \frac It is a mass-specific intrinsic property of the substance. It is the reciprocal of density (rho) ...

of the mixture. :

v = \sum_i w_i\cdot \bar = \frac

\sum_i \rho_i \cdot \bar = 1

References

Mass density {{Biochem-stub

Properties

See also

References