The Parkinson's Foundation is a national organization that funds research and provides educational resources to

Parkinson’s disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...

patients and caregivers. The Parkinson's Foundation was established in 2016 through the merger of the National Parkinson Foundation and the Parkinson's Disease Foundation. The Parkinson's Foundation has headquarters in

Miami Miami ( ), officially the City of Miami, known as "the 305", "The Magic City", and "Gateway to the Americas", is a East Coast of the United States, coastal metropolis and the County seat, county seat of Miami-Dade County, Florida, Miami-Dade C ...

and

New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...

, in addition to 17 chapters throughout the United States.

History

1957–1960s

The organizations that merged to create the Parkinson's Foundation in 2016 were both created in 1957. The National Parkinson Foundation was founded by Jeanne C. Levey in Miami and the Parkinson's Disease Foundation was founded by William Black in New York. The founding organizations funded researchers such as Melvin Yahr and

H. Houston Merritt Hiram Houston Merritt Jr. (January 12, 1902, Wilmington, North Carolina – January 9, 1979 in Boston, Massachusetts) was one of the pre-eminent academic neurologists of his day. He was chair of the Neurological Institute of New York and Neurolog ...

. In 1965, Parkinson's Foundation funding led to the establishment of the

Columbia University Medical Center NewYork-Presbyterian/Columbia University Irving Medical Center (NYP/CUIMC), also known as the Columbia University Irving Medical Center (CUIMC), is an academic medical center and the largest campus of NewYork-Presbyterian Hospital. It includes C ...

‘s basic science laboratories in the William Black Building. In 1969, Yahr and Parkinson's Foundation colleagues published results of the first double-blind trial of

levodopa -DOPA, also known as levodopa and -3,4-dihydroxyphenylalanine, is an amino acid that is made and used as part of the normal biology of some plants and animals, including humans. Humans, as well as a portion of the other animals that utilize -DOPA ...

1970s–1980s

The Parkinson's Foundation began funding summer fellowships for medical students in the 1970s. In 1971, Roger C. Duvoisin developed the Columbia University Rating Scale, the forerunner to the Unified Parkinson Disease Rating Scale. In the same year, the Parkinson's Foundation and Merck, Inc. funded Dr. Yahr's double-blind clinical trial of

carbidopa/levodopa Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. It is primarily used to manage the symptoms of Parkinson's disease, but it does not slow down the disease or stop it ...

(Sinemet®), which remains the gold standard therapy for Parkinson's disease. In the 1980s, the Parkinson's Foundation began investing in movement disorder training fellowships at

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...

and

Rush University Rush University is a private research university in Chicago, Illinois. The university, founded in 1972, is the academic arm of Rush University Medical Center. Rush University comprises: * Rush Medical College * Rush University College of Nursing ...

. In 1985, the Parkinson's Foundation established its Centers of Excellence Network, which today consists of 51 designated medical centers worldwide that deliver care to more than 196,000 Parkinson's patients.

1990s–2000s

With funding from the Parkinson's Foundation, Duvoisin and his team described the Contursi kindred – the first description of inherited Parkinson's – in 1990. In 1994, the Parkinson's Foundation joined several other organizations to create a scientific research fundraiser, the Parkinson's Unity Walk. In 2002, a research team at Columbia University funded by the Parkinson's Foundation found evidence that Parkinson's requires the alpha-synuclein protein, a now well-known hallmark of the disease.

2010s–2020s

In 2011, the Parkinson's Foundation launched Moving Day®, its signature fundraising walk for Parkinson's. In 2019, the Parkinson's Foundation launched PD GENEration, a national initiative that offers

genetic testing Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or ...

for clinically relevant Parkinson's-related genes and

genetic counseling Genetic counseling is the process of investigating individuals and families affected by or at risk of genetic disorders to help them understand and adapt to the medical, psychological and familial implications of genetic contributions to disease; t ...

at no cost for Parkinson's patients. In 2022, the Parkinson's Foundation partnered with

Parkinson's UK Parkinson's UK is a Parkinson's research and support charity in the United Kingdom. In April 2010, the Parkinson's Disease Society changed its name to become Parkinson's UK. Its aims are to improve the quality of life for people affected by Park ...

to establish the Venture Philanthropy Fund, which invests money into Parkinson's disease research.

Research

Clinical Studies

Parkinson's Outcomes Project

The Parkinson's Outcomes Project was started in 2009 and as of 2022 remains the largest-ever clinical study of Parkinson's disease. The longitudinal study is executed through the Parkinson's Foundation Global Care Network and monitors the symptoms and quality of life of Parkinson's patients to determine best practices in healthcare and establish standard treatment protocols. The Parkinson's Outcomes Project found that depression and anxiety are the number one factors impacting the overall health of Parkinson's patients. The study also found that increasing physical activity to at least 2.5 hours a week can slow decline in quality of life.

PD GENEration: Mapping the Future of Parkinson's Disease

PD GENEration: Mapping the Future of Parkinson's Disease is a national initiative that offers

for clinically relevant Parkinson's-related genes and

at no cost for Parkinson's patients.

Venture Philanthropy Fund

In 2022, the Parkinson's Foundation established the Venture Philanthropy Fund. This fund advances Parkinson's disease research by investing money into the Parkinson's Virtual Biotech Fund, the drug development arm of

Affiliations

Global Care Network

The Parkinson's Foundation Global Care Network is a healthcare network that provides care to Parkinson's patients. The network is composed of Centers of Excellence and Comprehensive Care Centers. A Parkinson's Foundation Center of Excellence is a medical center with a specialized team of

neurologists Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal ...

, movement disorder specialists,

physical therapists Physical therapy (PT), also known as physiotherapy, is one of the allied health professions. It is provided by physical therapists who promote, maintain, or restore health through physical examination, diagnosis, management, prognosis, patient ...

occupational therapist Occupational therapists (OTs) are health care professionals specializing in occupational therapy and occupational science. OTs and occupational therapy assistants (OTAs) use scientific bases and a holistic perspective to promote a person's abilit ...

mental health professional A mental health professional is a health care practitioner or social and human services provider who offers services for the purpose of improving an individual's mental health or to treat mental disorders. This broad category was developed as a ...

s and others who are up to date on the latest Parkinson's medications, therapies and research. The Foundation has designated 60 medical centers around the world as part of its Global Care Network. Parkinson's Foundation Comprehensive Care Centers are medical facilities with multi-disciplinary teams providing Parkinson's care. Each center is required to meet care, professional training, community education and outreach criteria. The Parkinson's Foundation is affiliated with the following institutions:

Research Centers

The Parkinson's Foundation has designated four institutions as research centers:

, the

University of Florida The University of Florida (Florida or UF) is a public land-grant research university in Gainesville, Florida. It is a senior member of the State University System of Florida, traces its origins to 1853, and has operated continuously on its ...

in collaboration with

Emory University Emory University is a private research university in Atlanta, Georgia. Founded in 1836 as "Emory College" by the Methodist Episcopal Church and named in honor of Methodist bishop John Emory, Emory is the second-oldest private institution of ...

, the

University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...

in collaboration with The University of Texas Southwestern Medical Center, and the

Yale School of Medicine The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary te ...

. These institutions receive $2 million in Parkinson's Foundation funding over four years to further research that advances the understanding and treatment of Parkinson's.

Grants and Awards

Since 1957, the Parkinson's Foundation has invested more than $425 million in Parkinson's disease research and clinical care.

Awards for Institutions

The Parkinson's Foundation Research Center designation provides funding for team science at institutions working on a thematic area of Parkinson's disease. The Institutional Movement Disorders Fellowship provides an institution with the funds to support the two-year long training of an incoming movement disorders fellow.

Awards for Independent Investigators

George G. Kaufman Impact Awards fund projects that are in need of support to impact the Parkinson's community. Stanley Fahn Junior Faculty Awards provide funding to early career scientists to further their Parkinson's disease research. Conference Awards support the gathering of experts working to address unsolved clinical or basic science problems relevant to Parkinson's disease.

Fellowships & Early Career Awards

The Launch Award is an award for postdoctoral researchers who are transitioning to independent research careers in Parkinson's. Postdoctoral Fellowships are two-year fellowships for scientists who have recently completed their Ph.D. training or neurology residencies. Visiting Scholar Awards support the travel and housing of scholars while visiting host laboratories that conduct Parkinson's research. Summer Student Fellowships provide students interested in Parkinson's disease with an opportunity to conduct research through 10 weeks of clinical or laboratory work. The Melvin Yahr Early Career Award in Movement Disorders Research supports neurologists after residency. Partnership Awards are collaborative partnerships supporting clinician-scientist training, patient-oriented Parkinson's research and medical student Parkinson's studies. The Nurse Faculty Award is seed grant funding intended to support Edmond J. Safra Visiting Nurse Scholars. The Physical Therapy Faculty Award is seed grant funding intended to support Physical Therapy Faculty alumni.

Advocacy

The Parkinson's Foundation partners with

The Michael J. Fox Foundation The Michael J. Fox Foundation for Parkinson's Research is dedicated to finding a cure for Parkinson's disease (PD) established in 2000 by Michael J. Fox. It concentrates on funding research and ensuring the development of improved therapies for ...

to host the Parkinson's Policy Forum. The event brings together community members and researchers for research updates, policy briefings, advocacy trainings and networking opportunities. The People with Parkinson's Advisory Council is a patient leadership group. The council was created in 2006 and is comprised of people with Parkinson's disease and caregivers who serve as advisors to the foundation. The Parkinson's Foundation Research Advocates program trains Parkinson's patients and their caregivers to collaborate with Parkinson's disease scientists in research. The program was established in 2008 and has trained more than 350 participants.

Programs and Services

Helpline

The Parkinson's Foundation Helpline is staffed by nurses, social workers and health educators. PD Conversations is an online support network that allows individuals to ask experts Parkinson's questions.

Newly Diagnosed

The Newly Diagnosed Kit includes information and resources for individuals who have recently been diagnosed with Parkinson's disease.

Aware in Care

The Aware in Care hospitalization kit provides information and resources to help Parkinson's patients stay safe during hospital visits.

Virtual Education Programming

Care Partner Program

The series of online courses provides Parkinson's caregivers with information and tools to help care for someone living with Parkinson's disease.

Expert Briefings Webinars

The webinars highlight the latest Parkinson's disease research and updates from experts in the field.

PD Health @ Home

The virtual educational and wellness program hosts weekly online events that provide at-home resources to Parkinson's patients and caregivers. Events include Mindfulness Mondays, Wellness Wednesdays and Fitness Fridays.

Substantial Matters: Life and Science of Parkinson's

The podcast series, hosted by Dan Keller, PhD, interviews Parkinson's experts to highlight treatments and techniques for living with Parkinson's disease, as well as research updates in the field.

Community Grant Program

The grants support education and outreach programs that address unmet needs in the Parkinson's community. Since 2011, the Parkinson's Foundation has invested more than $9.4 million in community-based programs.

Community events

Moving Day

Moving Day, a Walk for Parkinson's, is the main fundraising event for the Parkinson's Foundation. Moving Day was started in 2011 and hosts events in cities across the United States. The walk has raised over $40 million to advance Parkinson's disease research and improve care.

Parkinson's Champions

Parkinson's Champions is a community fundraising and endurance program. Individuals plan their own events or participate in endurance races to raise funds and awareness for Parkinson's disease. The program has raised nearly $12 million.

Parkinson's Revolution

Revolution is an annual indoor cycling event that raises funds to generate awareness and advance the mission of the Parkinson's Foundation. Revolution was started in 2020 and events take place in cities across the United States. The cycling event has raised over $565,000 to advance Parkinson's disease research and improve care.

Key people

John L. Lehr has been the chief executive officer since 2017. J. Gordon Beckham, Jr. serves as the chair of the Foundation's board of directors.

Mergers, acquisitions, and partnerships

In August 2016, PDF and NPF merged to form the Parkinson's Foundation. In October 2017, the Parkinson's Foundation acquired the Melvin Yahr International Parkinson's Disease Foundation. In January 2020, the Parkinson's Foundation partnered with Zelira Therapeutics to study the benefits of

medical cannabis Medical cannabis, or medical marijuana (MMJ), is cannabis and cannabinoids that are prescribed by physicians for their patients. The use of cannabis as medicine has not been rigorously tested due to production and governmental restrictions ...

in PD patients. In May 2020, the Parkinson's Foundation partnered with the

U.S. Department of Veteran Affairs The United States Department of Veterans Affairs (VA) is a Cabinet-level executive branch department of the federal government charged with providing life-long healthcare services to eligible military veterans at the 170 VA medical centers and ...

to increase access to information about Parkinson's disease. Veterans who develop Parkinson's disease can be associated with exposure to

Agent Orange Agent Orange is a chemical herbicide and defoliant, one of the "tactical use" Rainbow Herbicides. It was used by the U.S. military as part of its herbicidal warfare program, Operation Ranch Hand, during the Vietnam War from 1961 to 1971. It ...

or other herbicides during military service.

References

{{Authority control Parkinson's disease Medical and health foundations in the United States Neurology organizations Disability organizations based in the United States