In
enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, a pantetheine hydrolase () is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:(R)-pantetheine + H
2O
(R)-pantothenate + 2-aminoethanethiol
Thus, the two
substrates of this enzyme are
(R)-pantetheine and
H2O, whereas its two
products are
(R)-pantothenate and
2-aminoethanethiol.
This enzyme belongs to the family of
hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The
systematic name of this enzyme class is (R)-pantetheine amidohydrolase. Other names in common use include pantetheinase, vanin, and vanin-1. This enzyme participates in
pantothenate and coa biosynthesis
Pantothenic acid, also called vitamin B5 is a water-soluble B vitamin and therefore an essential nutrient. All animals require pantothenic acid in order to synthesize coenzyme A (CoA) – essential for fatty acid metabolism – as well as to, ...
.
References
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EC 3.5.1
Enzymes of unknown structure
{{3.5-enzyme-stub