Palazzo Pio can refer to:
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Palazzo Orsini Pio Righetti
The Palazzo Orsini Pio Righetti (also ''Palazzo Pio'') is a building in the Roman district of Parione. It was built around 1450 and lies on top of the ruins of the Temple of Venus Victrix of the Theatre of Pompey. In the 17th century the facade w ...
, a building erected on parts of the remains of the Theater of Pompey in Rome
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Palazzo Pio (Borgo), a building in the ''Borgo'' district of Rome and extraterritorial property of the Holy See. It hosts the Canadian and Taiwanese embassies to the Holy See.
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