The PTS Galactitol (Gat) Family
TC# 4.A.5 is part of the
PTS-AG superfamily
Permease of phosphotransferase system (or PTS-AG superfamily according to TCDB) is a superfamily of phosphotransferase enzymes that facilitate the transport of L-ascorbate (A) and galactitol
Galactitol (dulcitol) is a sugar alcohol, the red ...
. The biochemistry of this family is poorly defined. The only well-characterized member of this family is the galactitol permease of ''
Escherichia coli.'' However, a homologous IIC protein from ''
Listeria monocytogenes'' has been shown to be required for D-arabitol fermentation. It presumably functions together with IIA
Gat and IIB
Gat homologues. IIC
Gat is distantly related to IIC
Sgc of ''E. coli''; IIA
Gat is distantly related to IIA
Sga and IIA
Sgcof ''E. coli'' as well as IIA
Mtl and IIA
Fru. IIB
Gat is distantly related to IIB
Sga and IIB
Sgc of ''E. coli.'' Domains in the LicR/CelR family of
transcriptional activators show C-terminal domains exhibiting weak sequence similarity to IIB
Gat and IIA
Gat.
References
{{CCBYSASource, sourcepath=http://tcdb.org/search/result.php?tc=4.A.5, sourcearticle=4.A.5 The PTS Galactitol (Gat) Family
, revision=699838558
Prokaryote genes