Multiple hamartoma syndrome is a
syndrome
A syndrome is a set of medical signs and symptoms which are correlated with each other and often associated with a particular disease or disorder. The word derives from the Greek language, Greek σύνδρομον, meaning "concurrence". When a sy ...
characterized by more than one
hamartoma
A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended fr ...
.
It is sometimes equated with
Cowden syndrome. However,
MeSH
A mesh is a barrier made of connected strands of metal, fiber, or other flexible or ductile materials. A mesh is similar to a web or a net in that it has many attached or woven strands.
Types
* A plastic mesh may be extruded, oriented, exp ...
also includes Bannayan–Zonana syndrome (that is,
Bannayan–Riley–Ruvalcaba syndrome) and
Lhermitte–Duclos disease
Lhermitte–Duclos disease (LDD) (), also called dysplastic gangliocytoma of the cerebellum, is a rare, slowly growing tumor of the cerebellum, a gangliocytoma sometimes considered to be a hamartoma, characterized by diffuse hypertrophy of the ...
under this description. Some articles include Cowden syndrome, Bannayan–Riley–Ruvalcaba syndrome, and at least some forms of
Proteus syndrome
Proteus syndrome is a rare disorder with a genetic background that can cause tissue overgrowth involving all three embryonic lineages. Patients with Proteus syndrome tend to have an increased risk of embryonic tumor development.Freedberg, et al. ...
and
Proteus-like syndrome
Proteus-like syndrome (PLS) is a condition similar to Proteus syndrome, but with an uncertain cause.It's characterized by skeletal and hamartous overgrowth of multiple tissues, nevi in cerebriform connective tissue, blood vessel malformations and l ...
under the umbrella term PTEN hamartoma tumor syndromes (PHTS).
See also
*
PTEN (gene)
Phosphatase and tensin homolog (PTEN) is a phosphatase in humans and is encoded by the ''PTEN'' gene. Mutations of this gene are a step in the development of many cancers, specifically glioblastoma, lung cancer, breast cancer, and prostate ca ...
*
List of cutaneous conditions
*
List of syndromes
This is an alphabetically sorted list of medical syndromes.
starting with numbers.
#13q deletion syndrome
# 17q21.31 microdeletion syndrome
#1p36 deletion syndrome
# 1q21.1 deletion syndrome
#1q21.1 duplication syndrome
# 22q11.2 distal deletion ...
*
Characteristics of syndromic ASD conditions
Syndromic autism (or syndromic autism spectrum disorders) denotes cases of autism spectrum disorder that are associated with a broader medical condition, generally a syndrome. Cases without such association, which account for the majority of tota ...
References
External links
Epidermal nevi, neoplasms, and cysts
Syndromes affecting the skin
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