DNA polymerase epsilon subunit 2 is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the ''POLE2''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
POLE2 has been shown to
interact
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with
SAP18
Histone deacetylase complex subunit SAP18 is an enzyme that in humans is encoded by the ''SAP18'' gene.
Function
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are cat ...
.
References
Further reading
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External links
PDBe-KBprovides an overview of all the structure information available in the PDB for Human DNA polymerase epsilon subunit 2 (POLE2)
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