PNI may refer to:

Organizations

* Indonesian National Party (''Partai Nasional Indonesia''), the name used by several political parties in Indonesia * Palestinian National Initiative, a Palestinian political party * PNI Digital Media (Photochannel Networks Inc), a US company that operates an on-demand photographic printing service * United Nations Office on Drugs and Crime#Organizational structure, United Nations Crime Prevention and Criminal Justice Programme Network, a global research- and information-sharing network

Science

* Perineural invasion, cancer spreading along a nerve * Psychoneuroimmunology, the study of interaction between the nervous system and immune system

Technology

* Prescott New Instructions, also known as SSE3, an instruction set introduced with the Intel Prescott processor in 2004 * Private Network Interconnect, a method of Internet peering

Places

* PNI, IATA Airport Code for Pohnpei International Airport in Micronesia {{disambig