E3 ubiquitin-protein ligase Praja1 is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
that in humans is encoded by the ''PJA1''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Interactions
PJA1 has been shown to
interact
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with
UBE2D2
Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the ''UBE2D2'' gene.
Function
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degrad ...
and
MAGED1.
References
Further reading
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