PHA-57378 is a drug which acts as an agonist at
serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vas ...
5-HT
2 receptors, having a binding affinity of 4.1 nM at the
5-HT2A subtype and 4.3 nM at
5-HT2C. It has
anxiolytic effects in animal studies.
See also
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PNU-22394
PNU-22394 is a drug which acts as an agonist at serotonin 5-HT2 receptors, with strongest binding affinity for 5-HT2A and 5-HT2C and slightly weaker at 5-HT2B, although it is only a full agonist at 5-HT2C, but partial agonist at 5-HT2A and 5- ...
*
PNU-181731
PNU-181731 is a drug which acts as an agonist at serotonin 5-HT2 receptors, with strongest binding affinity for the 5-HT2C subtype at 4.8nM, and weaker 5-HT2A affinity of 18nM. It has anxiolytic effects in animal studies with around one tenth t ...
References
Serotonin receptor agonists
Tryptamines
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