PH-797804 is a drug which acts as a selective inhibitor of the enzyme

p38 mitogen-activated protein kinase p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell different ...

(p38 MAPK). It has antiinflammatory effects and has been researched for the treatment of inflammatory lung conditions such as

chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce ...

and

COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December ...

. While it has not been adopted for clinical use, it remains widely used in research.

References

{{pharm-stub Benzamides 2-Pyridones Fluoroarenes Bromoarenes Aromatic ethers

See also

References