Peroxisomal biogenesis factor 19 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''PEX19''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
PEX19 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
ABCD1
ABCD1 is a protein that transfers fatty acids into peroxisomes.
Function
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and in ...
,
[
* ]ABCD2
ATP-binding cassette sub-family D member 2 is a membrane pump/transporter protein that in humans is encoded by the ''ABCD2'' gene.
Function
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transpor ...
,[
* ABCD3,]PEX10
Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the ''PEX10'' gene. Alternative splicing results in two transcript variants encoding different isoforms.
Function
Peroxisome biogenesis factor 10 is involved in import o ...
,[
* ]PEX12
Peroxisome assembly protein 12 is a protein that in humans is encoded by the ''PEX12'' gene.
Function
PEX12 is needed for protein import into peroxisomes. This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essent ...
,[
* ]PEX13
Peroxisomal membrane protein PEX13 is a protein that in humans is encoded by the ''PEX13'' gene. It located on chromosome 2 next to KIAA1841
Interactions
PEX13 has been shown to interact with PEX14, PEX5 and PEX19
Peroxisomal biogenesis fact ...
,[
* PEX16,][ and
* PEX3.]
References
Further reading
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External links
GeneReviews/NCBI/NIH/UW entry on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum
OMIM entries on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum
* {{PDBe-KB2, P40855, Peroxisomal biogenesis factor 19