Photoreceptor phosphodiesterase 6 (PDE6 or PDE-6) is a protein complex family, which is highly concentrated in the
retina
The retina (from la, rete "net") is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then ...
.
See also
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cGMP
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PDE6A
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha is an enzyme that in humans is encoded by the ''PDE6A'' gene.
PDE6A encodes the cyclic-GMP ( cGMP) specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod ou ...
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PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta is the beta subunit of the protein complex PDE6 that is encoded by the ''PDE6B'' gene. PDE6 is crucial in transmission and amplification of visual signal. The existence of this beta subu ...
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PDE6C
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the ''PDE6C'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of ...
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PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta is an enzyme that in humans is encoded by the ''PDE6D'' gene. PDE6D was originally identified as a fourth subunit of rod cell-specific cGMP phosphodiesterase (PDE) ( ...
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PDE6G
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma is an enzyme that in humans is encoded by the ''PDE6G'' gene.
Interactions
PDE6G has been shown to interact with Beta adrenergic receptor kinase
G-protein-cou ...
References
{{Enzymes
EC 3.1.4