pComb3H, a derivative of pComb3 optimized for expression of human fragments, is a

phagemid A phagemid or phasmid is a DNA-based cloning vector, which has both bacteriophage and plasmid properties. These vectors carry, in addition to the origin of plasmid replication, an origin of replication derived from bacteriophage. Unlike commonly u ...

used to express proteins such as

zinc finger proteins A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold. It was originally coined to describe the finger-like appearance of a hypothesized struc ...

and antibody fragments on phage pili for the purpose of

phage display Phage display is a laboratory technique for the study of protein–protein, protein–peptide, and protein– DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes ...

selection. For the purpose of phage production, it contains the bacterial ampicillin resistance gene (for B-lactamase), allowing the growth of only transformed bacteria.

References

Molecular biology Plasmids {{Genetics-stub