The ''Staphylococcus'' phage P68 Putative Holin (P68 Hol) Family
TC# 1.E.38 consists of a single putative holin
TC# 1.E.38.1.1 from ''Staphylococcus aureus'' phage P68 that is 92 amino acyl residues (aas) in length and exhibits 2 transmembrane segments (TMSs).
While annotated as a holin, this protein has not been functionally characterized.
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See also
* Holin
* Lysin
Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target ...
* Transporter Classification Database
Further reading
* Reddy, Bhaskara L.; Saier Jr., Milton H. (2013-11-01)
"Topological and phylogenetic analyses of bacterial holin families and superfamilies"
''Biochimica et Biophysica Acta (BBA) - Biomembranes'' 1828 (11): 2654–2671. doi: 10.1016/j.bbamem.2013.07.004. PMC&nbs
3788059
PMID&nbs
23856191
* Saier, Milton H.; Reddy, Bhaskara L. (2015-01-01)
"Holins in Bacteria, Eukaryotes, and Archaea: Multifunctional Xenologues with Potential Biotechnological and Biomedical Applications"
''Journal of Bacteriology'' 197(1): 7–17. doi: 10.1128/JB.02046-14. ISSN&nbs
0021-9193
PMC&nbs
4288690
PMID&nbs
25157079
* Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01)
"Holins: the protein clocks of bacteriophage infections"
''Annual Review of Microbiology'' 54: 799–825. doi: 10.1146/annurev.micro.54.1.799. ISSN&nbs
0066-4227
PMID&nbs
11018145
* Young, R.; Bläsi, U. (1995-08-01)
"Holins: form and function in bacteriophage lysis"
''FEMS Microbiology Reviews'' 17 (1-2): 191–205. ISSN&nbs
0168-6445
PMID&nbs
7669346
References
{{CCBYSASource, sourcepath=http://tcdb.org/search/result.php?tc=1.E.38, sourcearticle=The Staphylococcus phage P68 Putative Holin (P68 Hol) Family, revision=699838558
Protein families
Membrane proteins
Transmembrane proteins
Transmembrane transporters
Transport proteins
Integral membrane proteins
Holins