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Organ transplantation in Japan is regulated by the 1997 Organ Transplant Law which legalized organ procurement from "
brain dead Brain death is the permanent, irreversible, and complete loss of brain function which may include cessation of involuntary activity necessary to sustain life. It differs from persistent vegetative state, in which the person is alive and some aut ...
" donors. After an early involvement in organ transplantation that was on a par with developments in the rest of the world, attitudes in Japan altered after a transplant by Dr. Wada in 1968 failed, and a subsequent ban on cadaveric
organ donation Organ donation is the process when a person allows an organ of their own to be removed and transplanted to another person, legally, either by consent while the donor is alive or dead with the assent of the next of kin. Donation may be for re ...
lasted 30 years. The first transplant after the Organ Transplant Law had defined "brain death" took place in February 1999. Due to cultural reasons and a relative distrust of
modern medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practice ...
, the rate of organ donation in
Japan Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north ...
is significantly lower than in Western countries.


History

The first organ transplant in Japan took place at
Niigata University is a national university in Niigata, Niigata Prefecture, Japan. It was established in 1949 and has its major origins in Niigata Medical College (established in 1922) and in Niigata Higher School (established in 1919). It is one of the largest Jap ...
in 1956 when a kidney was temporarily transplanted to a patient with acute renal failure. In 1964 a permanent and full-scale
kidney transplant Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). Kidney transplant is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantati ...
was successfully undertaken at the
University of Tokyo , abbreviated as or UTokyo, is a public research university located in Bunkyō, Tokyo, Japan. Established in 1877, the university was the first Imperial University and is currently a Top Type university of the Top Global University Project by ...
, and by 1992 nearly 9,000 kidney transplants had taken place. In the same year, a
liver transplant Liver transplantation or hepatic transplantation is the replacement of a Liver disease, diseased liver with the healthy liver from another person (allograft). Liver transplantation is a treatment option for Cirrhosis, end-stage liver disease and ...
was performed at
Chiba University is a national university in the city of Chiba, Japan. It offers Doctoral degrees in education as part of a coalition with Tokyo Gakugei University, Saitama University, and Yokohama National University. The university was formed in 1949 from exist ...
by Professor Komei Nakayama. The first heart transplant in Japan was conducted at
Sapporo Medical University is a public university in Chūō-ku, Sapporo, Hokkaidō, Japan. The precursor of the school was founded in 1945, and it was chartered as a university in 1950. History The , the precursor of the university, was founded in 1945. The Sapporo Medi ...
in 1968 by Dr Wada. This operation attracted concerns that Dr. Wada's evaluation of brain death was inappropriate, and even though an investigation of possible criminal liability was dismissed, a distrust of organ transplanting developed, particularly of transplants from brain dead donors. This brought subsequent developments in transplanting to a halt.


Cultural attitudes

The Japanese people's views regarding life, death, ethics and religion have influenced their negative attitude toward organ transplanting. The Wada heart transplant in 1968 increased a sense of apprehension, especially regarding the evaluation of brain death. The Shinto religion regards death as impure, and has tainted connotations which have carried through into Japanese culture.


References

{{Organ transplantation Healthcare in Japan
Japan Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north ...