Oxyclozanide is a

salicylanilide Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide. Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives includi ...

anthelmintic Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may a ...

. It is used in the treatment and control of

fascioliasis Fasciolosis is a parasitic worm infection caused by the common liver fluke ''Fasciola hepatica'' as well as by '' Fasciola gigantica''. The disease is a plant-borne trematode zoonosis, and is classified as a neglected tropical disease (NTD). It ...

ruminants Ruminants (suborder Ruminantia) are hoofed herbivorous grazing or browsing mammals that are able to acquire nutrients from plant-based food by fermenting it in a specialized stomach prior to digestion, principally through microbial actions. The ...

mainly domestic animals such as cattle, sheep, and goats. It mainly acts by uncoupling of

oxidative phosphorylation Oxidative phosphorylation (UK , US ) or electron transport-linked phosphorylation or terminal oxidation is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing chemical energy in order to produce adenosine tri ...

in flukes. Along with

niclosamide Niclosamide, sold under the brand name Niclocide among others, is an anthelmintic medication used to treat tapeworm infestations, including diphyllobothriasis, hymenolepiasis, and taeniasis. It is not effective against other worms such as flukes ...

, another

tapeworm Eucestoda, commonly referred to as tapeworms, is the larger of the two subclasses of flatworms in the class Cestoda (the other subclass is Cestodaria). Larvae have six posterior hooks on the scolex (head), in contrast to the ten-hooked Cestodar ...

drug, it has been recently found to display "strong ''in vivo'' and ''in vitro'' activity against methicillin-resistant ''Staphylococcus aureus'' (MRSA)". Sometimes alluded to as "''Pentaclosamide''": CN101891646.

References

Oxyclozanide MSDS
/ref> Anthelmintics Chloroarenes Phenols Salicylanilides {{antiinfective-drug-stub