Oxathiapiprolin (trade names Orondis,
Zorvec, and Segovis) is a
fungicide. In the United States, the
Environmental Protection Agency has approved it for use against several fungal diseases including
downy mildew
Downy mildew refers to any of several types of oomycete microbes that are obligate parasites of plants. Downy mildews exclusively belong to the Peronosporaceae family. In commercial agriculture, they are a particular problem for growers of cruc ...
and various ''
Phytophthora
''Phytophthora'' (from Greek (''phytón''), "plant" and (), "destruction"; "the plant-destroyer") is a genus of plant-damaging oomycetes (water molds), whose member species are capable of causing enormous economic losses on crops worldwide, a ...
'' species
including
late blight
''Phytophthora infestans'' is an oomycete or water mold, a fungus-like microorganism that causes the serious potato and tomato disease known as late blight or potato blight. Early blight, caused by ''Alternaria solani'', is also often called " ...
on crops including vegetables, ornamentals, and turf.
Its
mechanism of action
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. A mechanism of action usually includes mention of the specific molecular targ ...
involves binding to the
oxysterol-binding protein
The oxysterol-binding protein (OSBP)-related proteins (ORPs) are a family of lipid transfer proteins (LTPs). Concretely, they constitute a family of sterol and phosphoinositide binding and transfer proteins in eukaryotes that are conserved from ...
in
Oomycete
Oomycota forms a distinct phylogenetic lineage of fungus-like eukaryotic microorganisms, called oomycetes (). They are filamentous and heterotrophic, and can reproduce both sexually and asexually. Sexual reproduction of an oospore is the resul ...
s.
References
{{reflist, refs=
[{{cite web , title=Orondis - Fungicide Product & Label Information , website= Syngenta US , url=http://www.syngenta-us.com/fungicides/orondis , language=en , access-date=2021-03-24]
Fungicides
Fluoroarenes
Isoxazolines
Thiazoles
Piperidines
Pyrazoles
Trifluoromethyl compounds