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The Ottawa Hospital Research Institute (OHRI), formerly Ottawa Health Research Institute, is a non-profit academic health
research institute A research institute, research centre, research center or research organization, is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often i ...
located in the city of
Ottawa Ottawa (, ; Canadian French: ) is the capital city of Canada. It is located at the confluence of the Ottawa River and the Rideau River in the southern portion of the province of Ontario. Ottawa borders Gatineau, Quebec, and forms the core ...
. It was formed in 2001 following the merger of three Ottawa hospitals. The Ottawa Hospital Research Institute is the research arm of
The Ottawa Hospital The Ottawa Hospital (french: L'Hôpital d'Ottawa) is a hospital system in Ottawa, Ontario, Canada. The system was formed through the merger of the former Grace Hospital, Ottawa Riverside Hospital, Ottawa General Hospital and Ottawa Civic Hospital. ...
and affiliated with the
University of Ottawa The University of Ottawa (french: Université d'Ottawa), often referred to as uOttawa or U of O, is a bilingual public research university in Ottawa, Ontario, Canada. The main campus is located on directly to the northeast of Downtown Ottawa ...
. As of 2022, the Ottawa Hospital Research Institute houses approximately 2,200 scientists, clinician investigators, students, research fellows, and support staff. It has five research programs: Cancer Therapeutics; Chronic Disease; Clinical Epidemiology; Regenerative Medicine; and Neurosciences. Its researchers are studying more than a hundred different diseases, conditions and specialties with an overall focus on translating discoveries and knowledge into better health. Ronald G. Worton was the research institute's founding CEO and Scientific Director in 2001. In 2007, Duncan Stewart, formerly Chief Cardiologist of St. Michael's Hospital in Toronto and Director of Cardiology of
University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...
, took over as CEO and Scientific Director.


Notable Discoveries and Accomplishments

* Dr. Harold Atkins and Dr. Mark Freedman pioneered the use of autologous hematopoietic stem cell transplantation for the treatment of multiple sclerosis. * Dr. Michael Rudnicki was the first to characterize adult skeletal muscle stem cells. * Dr. Ian Stiell developed the
Ottawa Ankle Rules In medicine, the Ottawa ankle rules are a set of guidelines for clinicians to help decide if a patient with foot or ankle pain should be offered X-rays to diagnose a possible bone fracture. Before the introduction of the rules most patients with an ...
. * Dr. David Moher led the development of the
CONSORT __NOTOC__ Consort may refer to: Music * "The Consort" (Rufus Wainwright song), from the 2000 album ''Poses'' * Consort of instruments, term for instrumental ensembles * Consort song (musical), a characteristic English song form, late 16th–earl ...
reporting guidelines for clinical trials and the PRISMA reporting guidelines for systematic reviews and meta-analyses. * Dr. Doug Manuel develope
ProjectBigLife
a life expectancy calculator that helps educate people about healthy lifestyle choices. * Dr. John Bell and his colleagues demonstrated for the first time that an intravenously-delivered viral therapy can selectively infect and spread within tumours in humans. * Dr. Dean Fergusson and Dr. Paul Hebert discovered that aprotinin is associated with an increased risk of death compared to other drugs routinely used to prevent blood loss during heart surgery. * Dr. Annette O'Connor pioneered the use o
Patient Decision Aids
* Dr. Natasha Kekre is leading the first clinical trial of made-in-Canada CAR-T cells for the treatment of cance


Notable Faculty and Alumni

*
John Cameron Bell John Cameron Bell (born July 10, 1953 in Ancaster, Ontario) is a senior cancer researcher at the OHRI. He currently resides in Ottawa, Ontario with his wife Sheila. Education John received his Bachelor's degree and Ph.D. from McMaster University ...

Dean Fergusson

Ian Graham

Jeremy Grimshaw
*
Michael McBurney Michael may refer to: People * Michael (given name), a given name * Michael (surname), including a list of people with the surname Michael Given name "Michael" * Michael (archangel), ''first'' of God's archangels in the Jewish, Christian and ...
*
David Moher David Moher (born April 17, 1957) is an Irish epidemiologist and senior scientist in the Clinical Epidemiology Program at the Ottawa Hospital Research Institute (OHRI), where he is also Director of the for Journalology, and the Canadian EQUATOR ...
*
Annette O'Connor Annette Marie Cormier O'Connor (born 1950) is a distinguished professor and professor emerita at the School of Nursing at the University of Ottawa and a fellow of the Royal Society of Canada and Canadian Academy of Health Sciences. She is a Ti ...

Michael Rudnicki


References


External links


Official Site
{{authority control Medical research institutes in Canada Research in Ottawa University of Ottawa 2001 establishments in Ontario Educational institutions established in 2001