Osii may refer to:
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Asii
The Asii, Osii, Ossii, Asoi, Asioi, Asini or Aseni were an ancient Indo-European people of Central Asia, during the 2nd and 1st centuries BCE. Known only from Classical Greek and Roman sources, they were one of the peoples held to be responsible ...
, an ancient people of Bactria
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Osi (ancient tribe), an ancient people of Central Europe
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