Orthanilic acid (2-aminobenzenesulfonic acid) is a biological acid with roles in
benzoate
Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, wh ...
degradation and microbial metabolism in diverse environments.
Orthanilic acid promotes reverse turn formation in peptides, inducing a folded
conformation when incorporated into peptide sequences (Xaa-SAnt-Yaa), showing robust 11-membered-ring hydrogen-bonding.
Orthanilic acid is a structural component of some
azo dye
Azo dyes are organic compounds bearing the functional group R−N=N−R′, in which R and R′ are usually aryl and substituted aryl groups. They are a commercially important family of azo compounds, i.e. compounds containing the C-N=N ...
s which consequently have poor bacterial degradation.
Orthanilic acids have also been found to affect cardiac tension.
References
Benzenesulfonic acids
Amino acid derivatives
Anilines
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