Orla Hardiman
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Orla Hardiman (BSc MB BCh BAO MD FRCPI FAAN) is an Irish
consultant A consultant (from la, consultare "to deliberate") is a professional (also known as ''expert'', ''specialist'', see variations of meaning below) who provides advice and other purposeful activities in an area of specialization. Consulting servic ...
neurologist Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...
. She was appointed Professor of Neurology by Trinity College University of Dublin in 2014, where she heads the Academic Unit of Neurology, housed in Trinity Biomedical Sciences Institute. She is a HRB Clinician Scientist and Consultant Neurologist at the National Neuroscience Center of Ireland at Beaumont Hospital, Dublin. She leads a team of thirty researchers focusing on clinical and translational aspects of amyotrophic lateral sclerosis and related neurodegenerations. Hardiman has become a prominent advocate for neurological patients in Ireland, and for patients within the Irish health system generally. She is co-founder of the Neurological Alliance of Ireland and Doctors Alliance for Better Public Healthcare. In the past, she established the bi-annual ''Diaspora Meeting'', a forum for Irish neurologists based overseas to present and discuss their research findings with neurologists working in Ireland.American Academy of Neurology honours Dr. Orla Hardiman – IICN, Irish Institute of Clinical Neuroscience, Clinical Neurosciences Ireland, Irish Neuroscientists, Neuroscience Ireland, Brain Research Ireland
Iicn.ie.


Education and training


Undergraduate degree and early postgraduate training

Hardiman attended
University College Dublin University College Dublin (commonly referred to as UCD) ( ga, Coláiste na hOllscoile, Baile Átha Cliath) is a public research university in Dublin, Ireland, and a collegiate university, member institution of the National University of Ireland ...
(UCD) as an undergraduate medical student. She completed an intercalated BSc in
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
in 1980 and received her medical degree in 1983.http://www.cneuro.co.cu/files/Congreso.%20Curriculum/Orla%20Hardiman/Orla%20Hardiman.doc After graduation from UCD, Hardiman undertook a one-year
internship An internship is a period of work experience offered by an organization for a limited period of time. Once confined to medical graduates, internship is used practice for a wide range of placements in businesses, non-profit organizations and gover ...
at
St. Vincent's University Hospital St. Vincent's Hospital ( ga, Ospidéal Ollscoile Naomh Uinseann) is a teaching hospital located at Elm Park, south of the city of Dublin, Ireland. It is at the junction of Merrion Road and Nutley Lane opposite the Merrion Centre, Dublin, Merrion ...
, Dublin. From 1984 to 1986, she trained as a senior house officer in neurology and
neuropathology Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the clinic ...
at St. Lawrence's Hospital, Dublin.


United States

In 1986, Hardiman began a three-year neurology
residency Residency may refer to: * Domicile (law), the act of establishing or maintaining a residence in a given place ** Permanent residency, indefinite residence within a country despite not having citizenship * Residency (medicine), a stage of postgrad ...
under the Harvard Longwood Area Neurology Training Program at
Brigham and Women's Hospital Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts Gener ...
, Beth Israel Hospital and
Children's Hospital Boston Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical Sch ...
. In 1989, she undertook a two-year Clinical and Research Fellowship in Neuromuscular Diseases under Dr. Robert H. Brown Jr. at the Department of Neurology,
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
and
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
.


Return to Ireland

Upon completion of her fellowship, Hardiman took up a position as a Newman Scholar at the Department of Physiology in UCD. In 1992, Hardiman obtained her
medical doctorate Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
(MD) from UCD. She became a member of the
Royal College of Physicians of Ireland The Royal College of Physicians of Ireland (RCPI), ( ga, Coláiste Ríoga Lianna na hÉireann) is an Irish professional body dedicated to improving the practice of general medicine and related medical specialities, chiefly through the accredit ...
in 1993 and became a
fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...
of the College in 2001. In 1993 she became director of the ALS and neuromuscular clinics at Beaumont Hospital. In 1994 she was appointed as a tenured lecturer at the UCD Department of Physiology. She was appointed to Beaumont Hospital as the 11th Consultant Neurologist in Ireland in 1996. She held the position of Director of Neurology at Beaumont Hospital from 2000 to 2007, and has once more held it from 2012 to date. She was appointed as a Health Research Board Clinician Scientist and Clinical Professor of Neurology at Trinity College Dublin (2007). Hardiman is former Dean (2011-2013) of the Irish Institute of Clinical Neuroscience. She is the only Irish-based fellow of the
American Academy of Neurology The American Academy of Neurology (AAN) is a professional society representing over 38,000 neurologists and neuroscientists. As a medical specialty society it was established in 1948 by A.B. Baker of the University of Minnesota to advance the ar ...
.


Research

Hardiman is a
Health Research Board The Health Research Board (HRB) is a government agency responsible for funding, co-ordination, and oversight of medical research in Ireland. History In 1986, the Government of Ireland amalgamated the Medical Research Council of Ireland and the Medi ...
clinician scientist.
/ref> Her main research interests are
amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the progressive loss of motor neurons that control voluntary muscles. ALS is the most comm ...
(motor neurone disease) and related motor neuron degenerations,
phenotype In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological proper ...
/
genotype The genotype of an organism is its complete set of genetic material. Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have in a ...
correlations, population
genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar wor ...
and clinical
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
. Along with RCSI research fellow Dr. Matt Greenway, Hardiman discovered ''angiogenin'', a novel gene which may be responsible for motor neuron disease.Degenerative disease discovery
irishhealth.com.
The discovery led to the development of an international research programme with
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
, institutes in the United Kingdom and researchers at RCSI. Since 2008 she has been the editor in chief of the field journal "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration" and with Colin P Doherty is Co-Editor of the textbook "Neurodegenerative Disorders".


Awards and honours

In 2004, Hardiman received the first ''Palatucci Advocacy Leader of the Year Award'' from the
American Academy of Neurology The American Academy of Neurology (AAN) is a professional society representing over 38,000 neurologists and neuroscientists. As a medical specialty society it was established in 1948 by A.B. Baker of the University of Minnesota to advance the ar ...
. The selection committee commended her "tireless advocacy efforts on behalf of the neurology profession and patients" in Ireland. In 2009, she was awarded the Sheila Essey Award for ALS research by the American Academy of Neurology and the American ALS Association. She is the only Irish based neurologist to have received these awards from the American Academy of Neurology. In 2011 she received the Forbes Norris Award from the International Alliance of ALS/MND. The Award is to encourage a combination of two major qualities, management of and research into the disease to the benefit of people living with ALS/MND.


Patient advocacy

Hardiman has been an outspoken critic of clinics using stem cell therapy to treat neurological diseases, claiming it is "only at a very basic stage, even the animal experiments have not been proven", and comparing those offering the treatments to "19th century carpetbaggers". In 2006, Hardiman told a Joint Oireachtas Committee on Health and Children that the
Health Service Executive The Health Service Executive (HSE) ( ga, Feidhmeannacht na Seirbhíse Sláinte) is the publicly funded healthcare system in Ireland, responsible for the provision of health and personal social services. It came into operation on 1 January 2005 ...
was doing a "bad job" in treating people with chronic diseases who had to access emergency departments. In 2014 in her role as co-founder and spokesperson for the Neurological Alliance of Ireland she welcomed steps from the Irish government to restore governmental funding for organizations which support people living with Alzheimer's disease, Huntington's disease, and motor neurone disease.


References

{{DEFAULTSORT:Hardiman, Orla Living people Irish neurologists Year of birth missing (living people) Members of the Royal College of Physicians of Ireland Fellows of the Royal College of Physicians of Ireland Fellows of the American Academy of Neurology Place of birth missing (living people)