Opium Tea
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Poppy tea is an herbal tea infusion brewed from poppy straw or
seeds A seed is an embryonic plant enclosed in a protective outer covering, along with a food reserve. The formation of the seed is a part of the process of reproduction in seed plants, the spermatophytes, including the gymnosperm and angiosperm pl ...
of several species of poppy. The species most commonly used for this purpose is '' Papaver somniferum'', which produces
opium Opium (or poppy tears, scientific name: ''Lachryma papaveris'') is dried latex obtained from the seed capsules of the opium poppy ''Papaver somniferum''. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which i ...
as a natural defense against predators. In the live flower, opium is released when the surface of the bulb, called the seed pod, is pierced or scraped. For the purpose of the tea, dried pods are more commonly used than the pods of the live flower. The walls of the dried pods contain
opiate An opiate, in classical pharmacology, is a substance derived from opium. In more modern usage, the term ''opioid'' is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonis ...
alkaloids, primarily consisting of morphine. The tea is consumed for its
narcotic The term narcotic (, from ancient Greek ναρκῶ ''narkō'', "to make numb") originally referred medically to any psychoactive compound with numbing or paralyzing properties. In the United States, it has since become associated with opiates ...
effect, and in small amounts for
analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
, anti-diarrheal, and
sedative A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but t ...
effects. It has also been known to be used as a method of relieving withdrawal symptoms. Use of such preparations originated in parts of Central and Eastern Europe, the Levant and Near East, and Central and South Central Asia millennia ago. This tea is depicted both in Asian literature,
Western literature Western literature, also known as European literature, is the literature written in the context of Western culture in the languages of Europe, as well as several geographically or historically related languages such as Basque and Hungarian, an ...
, and is depicted as being available in opium dens.


Legality


Netherlands

In the Netherlands, all parts of ''Papaver somniferum'' after harvesting (except for the seeds) are illegal by law, as they are Listed as drugs in the Opium Law. Because of use for decorative purposes, the trade in, and possession of dried ''Papaver somniferum'' is not actively prosecuted. Trade in, or possession of dried ''Papaver somniferum'' with the intention of drug use can be prosecuted. The dried seed pod of ''Papaver somniferum'' is easily obtainable as it is commonly available for decorative use. Many varieties, strains, and cultivars of ''Papaver somniferum'' are in existence, and the alkaloid content can vary significantly.


United States

In the United States it is legal to purchase
poppy seed Poppy seed is an oilseed obtained from the opium poppy (''Papaver somniferum''). The tiny, kidney-shaped seeds have been harvested from dried seed pods by various civilizations for thousands of years. It is still widely used in many countries, ...
s, but all other parts of the plant are considered Schedule II controlled substances under the federal Controlled Substance Act of 1970. Unwashed poppy seeds used to make poppy tea may contain lethal concentrations of morphine and
codeine Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically use ...
. The Opium Poppy Exclusion Act of 1942 bans growing the poppy in many cases but is generally not a problem for gardeners as the plant is widely grown for the flowers and for seeds for replanting and cooking. For much of US history poppies were a significant cash crop, and the government encouraged farmers to grow more poppies for medicinal use during wars up to World War I. It is, however, manufacture of a schedule II substance to create a drink for the opium content, and the possession of it is illegal as well.


Canada

The import and sale of opium poppy seeds is legal in Canada, but possession of other parts of the plant may be prosecuted. Canadian authorities have noted the presence of dode or doda in the South Asian community, a traditional form of poppy tea. Crackdowns on this traditional preparation in the late 2000s led to a number of arrests in Canada.


Chemical composition

Poppy tea contains two groups of alkaloids:
phenanthrene Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) with formula C14H10, consisting of three fused benzene rings. It is a colorless, crystal-like solid, but can also appear yellow. Phenanthrene is used to make dyes, plastics and pesticides, e ...
s (including morphine and
codeine Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically use ...
) and
benzylisoquinoline Substitution of the heterocycle isoquinoline at the C1 position by a benzyl group provides 1‑benzylisoquinoline, the most widely examined of the numerous benzylisoquinoline structural isomers. The 1-benzylisoquinoline moiety can be identified wi ...
s (including papaverine). Of these, morphine is the most prevalent comprising 8%-14% of the total. Its effects derive from the fact that it binds to and activates mu opioid receptors in the brain, spinal cord, stomach and
intestine The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans ...
. Dried ''Papaver somniferum'' capsules and stems will, if harvested and dried by the usual protocol, contain significantly lower quantities of thebaine than opium made from latex as well as somewhat more codeine. When ingested, thebaine causes nausea, vomiting, and myoclonus. Thebaine is an important precursor for manufacture of pharmaceuticals, and is more concentrated in the roots of ''Papaver somniferum'' than elsewhere. Other species of poppies, numbering in the hundreds, do not contain morphine or codeine in useful amounts, but may contain non-narcotic alkaloids like protopine, sanguinarine or
berberine Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as ''Berberis vulgaris'' (barberry), ''Berberis aristata'' (tree turmeric), ''Mahonia aquifolium'' (Oregon grape), ''Hydra ...
.


Side effects and tolerance

Side effects increase with dosage and include drowsiness, mild stomach ache, lethargy, urinary retention,
bradypnea Bradypnea is abnormally slow breathing. The respiratory rate at which bradypnea is diagnosed depends on the age of the person, with the limit higher during childhood. Age ranges * Age 0–1 year < 30 breaths per minute * Age 1–3 years < 25 br ...
, constipation, nausea, respiratory depression and death. Nausea can be attributed to the presence of noscapine and is more common in first-time or inexperienced users. At high doses, the side effects are dangerous and can cause death through
respiratory arrest Respiratory arrest is a sickness caused by apnea (cessation of breathing) or respiratory dysfunction severe enough it will not sustain the body (such as agonal breathing). Prolonged apnea refers to a patient who has stopped breathing for a long p ...
or inhalation of vomit. Constipation often results from use, as with any opiate. Poppy tea is highly variable in potency; this accounts for almost all deaths related to the substance. Assume the tea is a saturated morphine solution when choosing the appropriate dose. Morphine's solubility in water is around 60mgs/ml. Additionally, frequent use results in high tolerance and dependence.
Chemical dependency Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has develope ...
builds in relation to the frequency of use, dosage, age, sex, weight and medical condition. Once chemical dependency has developed, abrupt cessation of use will cause
withdrawal Withdrawal means "an act of taking out" and may refer to: * Anchoresis (withdrawal from the world for religious or ethical reasons) * ''Coitus interruptus'' (the withdrawal method) * Drug withdrawal * Social withdrawal * Taking of money from a ban ...
; symptoms include leg and abdominal cramps,
mydriasis Mydriasis is the dilation of the pupil, usually having a non-physiological cause, or sometimes a physiological pupillary response. Non-physiological causes of mydriasis include disease, trauma, or the use of certain types of drugs. Normally, as ...
, vomiting, diarrhea,
headache Headache is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of depression in those with severe headaches. Headaches can occur as a result ...
, insomnia, cravings, lethargy and anxiety. Symptoms of withdrawal usually fade after 4–10 days but cravings and psychological dependence may continue for longer, in some cases up to a year. Treatment methods for addiction are generally the same for any opioid.


Deaths

In the United States, in 2003, a 17 year old who, according to his parents, was self-treating his anxiety with home-brewed poppy seed tea, died of pulmonary edema caused by acute morphine and codeine intoxication. A Drug Alert posted by the DOJ in 2010 pointed to five deaths possibly resulting from drinking of poppy tea. Since 2010, not less than 10 deaths presumably related to poppy tea consumption were reported by the
FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food s ...
's Center for Food Safety and Applied Nutrition Adverse Event Reporting System (CAERS). In Canada, on 19 May 2012, a 19-year-old from Nova Scotia died after drinking the tea from a poppy seed pod he purchased on the Internet. In November 2012, a Tasmanian youth died after drinking tea brewed from seed heads, and a 50-year-old Tasmanian man died in similar circumstances in February 2011. Some instances of death or injury associated with the consumption of poppy seed tea have involved users who combined the beverage with other nervous system depressants (i.e. alcohol, tranquillizers, benzodiazepines)Bailey, K., Clay, D., Kraner, J., et al. (2010, Oct.). Fatality Involving the Ingestion of Phenazepam and Poppy Seed Tea. ''Journal of Analytical Toxicology, 34'' (8), 527-573.


References

{{DEFAULTSORT:Poppy Tea Medicinal plants Opioids Poppy seeds Euphoriants Opium culture