The Open Notebook Science Challenge is a

crowdsourcing Crowdsourcing involves a large group of dispersed participants contributing or producing goods or services—including ideas, votes, micro-tasks, and finances—for payment or as volunteers. Contemporary crowdsourcing often involves digita ...

research project which collects measurements of the non-aqueous solubility of organic compounds and publishes these as open data; findings are reported in an

open notebook science Open-notebook science is the practice of making the entire primary record of a research project publicly available online as it is recorded. This involves placing the personal, or laboratory, notebook of the researcher online along with all raw and ...

manner. Although anyone may contribute research data, the competition is only open to post-secondary students in the US and UK. The challenge in turn forms part of the UsefulChem project, an ongoing

effort to synthesize and screen potential new anti-malarial drugs.UsefulChem
/ref> Data from the Solubility Challenge will be used to build predictive computational models of solubility for use in optimising syntheses.ONS solubility modeling and prediction
/ref> The challenge began on September 28, 2008
/ref> and, as of February 2014, involves researchers and their students from at least 4 different institutionsList of experiments
/ref> and has resulted in the acquisition of over 7672 solubility measurements. xsrv7.oru.edu/~alang/onsc/chemspace/cs.php Solubility of Organic Compounds in Organic Solvents/ref>

Prizes

To encourage participation, each month an awardA News Story Discussing the Awards
/ref> is given to the student who does, in the opinion of the judges,ONS Challenge judges
/ref> the best work. In order to participate, students have to be a US or UK resident.ONS Challenge Rules
/ref> The award is a US$500 cash prize. The first three winners also received a year's subscription to the journal '' Nature''. The awards are sponsored by Submetasubmeta
/ref> and ''Nature''.

Request an experiment

As well as concentrating on compounds related to the Ugi reaction, the ONSchallenge allows anyone to request a solubility measurement experiment. xsrv7.oru.edu/~alang/onsc/solubility/solubility.php request a solubility measurement experiment/ref>

Chemical donations

Sigma Aldrich Sigma-Aldrich (formally MilliporeSigma) is an American chemical, life science, and biotechnology company that is owned by the German chemical conglomerate Merck Group. Sigma-Aldrich was created in 1975 by the merger of Sigma Chemical Company ...

is also an official sponsor of the Open Notebook Science Challenge. Sigma Aldrich is participating by donating and shipping requested chemicals to any experimenters in the US or UKSigma Aldrich's involvement with the ONS challenge
/ref> for free.

References

External links

Open Notebook Science Challenge
{{dead link, date=February 2024 Open science Open data Crowdsourcing