Opaganib (ABC294640) is a drug which acts as an
inhibitor of the enzyme
sphingosine kinase
Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate, are ...
2. It is under development as a potential treatment agent for several different kinds of
cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
.
References
{{antineoplastic-drug-stub
Antineoplastic and immunomodulating drugs