Oncomodulin 2, also known as OCM2, is a human
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
that is similar to
oncomodulin
Oncomodulin is a parvalbumin-family calcium-binding protein expressed and secreted by macrophages (that typically traffic to tissue as an inflammatory response or after injury).
Oncomodulin is present in the eye.R&D Systems. 2015. ''Oncomodulin: ...
.
Oncomodulin
Oncomodulin is a parvalbumin-family calcium-binding protein expressed and secreted by macrophages (that typically traffic to tissue as an inflammatory response or after injury).
Oncomodulin is present in the eye.R&D Systems. 2015. ''Oncomodulin: ...
is a high-affinity
calcium ion-binding protein. It belongs to the superfamily of
calmodulin
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the bind ...
proteins, also known as the
EF-hand proteins. Oncomodulin 2 is an oncodevelopmental protein found in early embryonic cells in the
placenta
The placenta is a temporary embryonic and later fetal organ that begins developing from the blastocyst shortly after implantation. It plays critical roles in facilitating nutrient, gas and waste exchange between the physically separate mater ...
and also in
tumors
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
.
References
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