ATP synthase delta subunit is a subunit of

bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometr ...

l and chloroplast

F-ATPase F-ATPase, also known as F-Type ATPase, is an ATPase/ synthase found in bacterial plasma membranes, in mitochondrial inner membranes (in oxidative phosphorylation, where it is known as Complex V), and in chloroplast thylakoid membranes. It uses ...

/ synthase. It is known as OSCP (

oligomycin Oligomycins are macrolides created by ''Streptomyces'' that can be poisonous to other organisms. Function They have use as antibiotics. Oligomycin A is an inhibitor of ATP synthase. In oxidative phosphorylation research, it is used to prevent ...

sensitivity conferral

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...

) in mitochondrial ATPase (note that in mitochondria there is a different delta subunit, ATP synthase delta/epsilon subunit). The OSCP/delta subunit appears to be part of the peripheral stalk that holds the F₁ complex alpha3beta3 catalytic core stationary against the

torque In physics and mechanics, torque is the rotational equivalent of linear force. It is also referred to as the moment of force (also abbreviated to moment). It represents the capability of a force to produce change in the rotational motion of th ...

of the rotating central stalk, and links subunit A of the F_O complex with the F₁ complex. In mitochondria, the peripheral stalk consists of OSCP, as well as F_O components F6, B and D. In bacteria and chloroplasts the peripheral stalks have different subunit compositions: delta and two copies of F_O component B (bacteria), or delta and F_O components B and B' (chloroplasts). F-ATPases lacking this subunit generally transport sodium instead of protons. They are proposed to be called N-ATPases, since they seem to form a distinct group that is further apart from usual F-ATPases than A-ATPases are from V-ATPases. Human delta subunit of ATP synthase is coded by

gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...

ATP5O ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ''ATP5PO'' gene. The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix In the mitochondrion, the matrix is t ...

References

Further reading