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Ola Didrik Saugstad (born 5 March 1947) is a Norwegian pediatrician,
neonatologist Neonatology is a subspecialty of pediatrics that consists of the medical care of newborn infants, especially the ill or premature newborn. It is a hospital-based specialty, and is usually practised in neonatal intensive care units (NICUs). The ...
and
neuroscientist A neuroscientist (or neurobiologist) is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, neural circuits, and glial ...
noted for his research on resuscitation of newborn children and his contribution to reduce child mortality. He is a
Research Professor Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors ...
at
Oslo University Hospital Oslo University Hospital ( no, Oslo universitetssykehus; OUS) is a university hospital in Oslo, Norway. With over 24,000 employees it is the largest hospital organization in Europe. It is affiliated with the Faculty of Medicine of the University ...
and Professor of Neonatology at
Northwestern University Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Charte ...
's
Feinberg School of Medicine Northwestern University Feinberg School of Medicine is the medical school of Northwestern University and is located in the Streeterville neighborhood of Chicago, Illinois. Founded in 1859, Feinberg offers a full-time Doctor of Medicine degree p ...
in Chicago. He is Professor Emeritus of Pediatrics at the
University of Oslo The University of Oslo ( no, Universitetet i Oslo; la, Universitas Osloensis) is a public research university located in Oslo, Norway. It is the highest ranked and oldest university in Norway. It is consistently ranked among the top universit ...
and was Director of the Department of Pediatric Research at Oslo University Hospital from 1991 to 2017. He is a "world renowned expert in neonatal medicine," particularly on hypoxia and
purine Purine is a heterocyclic aromatic organic compound that consists of two rings ( pyrimidine and imidazole) fused together. It is water-soluble. Purine also gives its name to the wider class of molecules, purines, which include substituted purines ...
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run c ...
, hypoxia-reoxygenation injury, the effect and mechanisms of
oxygen radicals In chemistry, a radical, also known as a free radical, is an atom, molecule, or ion that has at least one unpaired valence electron. With some exceptions, these unpaired electrons make radicals highly chemically reactive. Many radicals spon ...
in the neonatal period, mechanisms of lung injury and newborn resuscitation. In 2010, international guidelines for newborn resuscitation were amended, based on the research of Saugstad and his colleagues, to recommend the use of air in place of pure oxygen, a discovery that is estimated to save the lives of 200,000 newborn children each year.Elin Fugelsnes
Kan redde 200 000 nyfødte
'' forskning.no'', 19 October 2010
He is an advisor to the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of ...
on child mortality. Saugstad has been cited over 23,000 times in scientific literature. The
NRK NRK, an abbreviation of the Norwegian ''Norsk Rikskringkasting AS'', generally expressed in English as the Norwegian Broadcasting Corporation, is the Norwegian government-owned radio and television public broadcasting company, and the largest ...
describes him as "the most internationally recognized and most widely cited Norwegian pediatrician of all times." Saugstad received the 2012 Nordic Medical Prize, is a member of the
Norwegian Academy of Science and Letters The Norwegian Academy of Science and Letters ( no, Det Norske Videnskaps-Akademi, DNVA) is a learned society based in Oslo, Norway. Its purpose is to support the advancement of science and scholarship in Norway. History The Royal Frederick Unive ...
and became a Knight First Class of the Order of St. Olav in 2010. His 2019 book ''Kampen om oksygenet'' ("The War Over Oxygen") discusses what he describes as "one fthe greatest scandals in the history of medicine;" former Prime Minister
Kjell Magne Bondevik Kjell Magne Bondevik (; born 3 September 1947) is a Norwegian Lutheran minister and politician. As leader of the Christian Democratic Party, he served as the 33rd prime minister of Norway from 1997 to 2000, and from 2001 to 2005, making him, af ...
introduced the book when it was released at the House of Literature in Oslo.


Background

Ola Didrik Saugstad is a son of the psychologist Per Saugstad and a grandson of the former rector of the University of Oslo
Didrik Arup Seip Didrik Arup Seip (31 August 1884 – 3 May 1963) was a professor of North Germanic languages at the University of Oslo. He earned his doctorate ( dr.philos.) in 1916 and was appointed professor the same year, retiring in 1954. Together with Herman ...
. His father earned a PhD in psychology at the
University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private university, private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park, Chicago, Hyde Park neighborhood. The University of Chic ...
in 1952, before he became a professor of psychology at the University of Oslo, and was noted for introducing an experimental approach to psychology in Norway, influenced by American psychology. Ola Didrik Saugstad is the brother of Jens Saugstad, a professor of philosophy at the University of Oslo.


Career

He graduated with the cand. med. degree at the
University of Oslo The University of Oslo ( no, Universitetet i Oslo; la, Universitas Osloensis) is a public research university located in Oslo, Norway. It is the highest ranked and oldest university in Norway. It is consistently ranked among the top universit ...
in 1973. Already as a medical student he became interested in the Swedish professor
Gösta Rooth Gösta Rooth (born 17 December 1918 in Stockholm, died 21 February 2008) was a Swedish physician and a pioneer of perinatal medicine. He graduated as a physician at Lund University in 1945 and obtained his PhD, also at Lund, in 1949. He became r ...
's research in the field of
perinatal Prenatal development () includes the development of the embryo and of the fetus during a viviparous animal's gestation. Prenatal development starts with fertilization, in the germinal stage of embryonic development, and continues in fetal devel ...
medicine and especially intrauterine
asphyxia Asphyxia or asphyxiation is a condition of deficient supply of oxygen to the body which arises from abnormal breathing. Asphyxia causes generalized hypoxia, which affects primarily the tissues and organs. There are many circumstances that ca ...
, and Rooth invited him to come to Sweden and do research; thus, after graduation he was a research fellow at Uppsala University Hospital. The research he carried out under Rooth's mentorship laid the foundation for his doctoral dissertation in 1977, ''Hypoxanthine as an Indicator of Hypoxia'', and for what would become his major research interest. From 1980 to 1981 he was a Fogarty International Fellow at the Department of Neonatology of the
University of California, San Diego The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Institution of Oceanography, UC San Diego is t ...
, in the unit of the legendary professor Louis Gluck, known as the father of neonatology. Saugstad was appointed senior consultant in newborn medicine at
Rikshospitalet Oslo University Hospital, Rikshospitalet is one of the four main campuses of Oslo University Hospital in Oslo, Norway. It was an independent hospital, ''Rigshospitalet'', later spelled ''Rikshospitalet'' ("The National Hospital"), from 1826 to 200 ...
in 1986. In 1991, he also became Professor of Pediatrics and Director of the Department of Pediatric Research at the
University of Oslo The University of Oslo ( no, Universitetet i Oslo; la, Universitas Osloensis) is a public research university located in Oslo, Norway. It is the highest ranked and oldest university in Norway. It is consistently ranked among the top universit ...
. From 2002 to 2004 he was President of the European Association of Perinatal Medicine. He was a board member of the European Society of Pediatric Research from 1987 to 1990, and of the International Pediatric Foundation from 2001 to 2004.Christian P. Speer, Henry L. Halliday
Laudatio: Ola Didrik Saugstad – An Oxygen Radical
'' Neonatology'' 2008;94:188–189.
Saugstad retired as Professor of Medicine and Director of the Department of Pediatric Research at the end of 2017. From 2017 he is affiliated with
Oslo University Hospital Oslo University Hospital ( no, Oslo universitetssykehus; OUS) is a university hospital in Oslo, Norway. With over 24,000 employees it is the largest hospital organization in Europe. It is affiliated with the Faculty of Medicine of the University ...
as a
research professor Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors ...
. In 2018 he was also appointed as Professor of Neonatology at the
Feinberg School of Medicine Northwestern University Feinberg School of Medicine is the medical school of Northwestern University and is located in the Streeterville neighborhood of Chicago, Illinois. Founded in 1859, Feinberg offers a full-time Doctor of Medicine degree p ...
in Chicago.


Research

In 1980, Saugstad was the first to demonstrate that oxygenation after a period of asphyxia could result in an explosive increase in
oxygen radicals In chemistry, a radical, also known as a free radical, is an atom, molecule, or ion that has at least one unpaired valence electron. With some exceptions, these unpaired electrons make radicals highly chemically reactive. Many radicals spon ...
. In the late 1980s, Saugstad and Rooth published a seminal article questioning the use of 100% oxygen in the resuscitation of newborn children. This would lead to his major discovery of the dangers of using 100% oxygen, resulting in the amendment of the international guidelines for newborn resuscitation in 2010 based on the research of Saugstad and his team. Saugstad has described the use of 100% oxygen as "one of the largest scandals in the history of medicine." It is estimated that his discovery can save the lives of 200,000 children each year. He has published more than 500 articles and book chapters in journals and books. He has served as an editor or a member of the editorial boards of several journals. According to Google Scholar, his work has been cited over 23,000 times in scientific literature, and he has an
h-index The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as ...
of 77.Ola Didrik Saugstad
''Google Scholar''
His 2019 book ''Kampen om oksygenet'' ("The War Over Oxygen") discusses what he describes as "one fthe greatest scandals in the history of medicine;" former Prime Minister
Kjell Magne Bondevik Kjell Magne Bondevik (; born 3 September 1947) is a Norwegian Lutheran minister and politician. As leader of the Christian Democratic Party, he served as the 33rd prime minister of Norway from 1997 to 2000, and from 2001 to 2005, making him, af ...
introduced the book when it was released at the House of Literature in Oslo. Saugstad is known for having taken elements of the research of 2019's Nobel laureates in medicine William Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza to the infant's bedside.


Awards and recognitions

* The Laerdal Award in Acute Medicine, 1995 (University of Oslo) * The Arvo Ylppö Medal in Neonatology, 1997 (University of Helsinki) * Fellow, Royal College of Physicians Edinburgh, 1997 * Honorary member of the Hungarian Paediatric Association, 2000 * Honorary member of the Norwegian Perinatal Society, 2001 * The Virginia Apgar Prize, 2001 * Honorary member of the Finnish Perinatal Society, 2005 * Honorary member of the European Association of Perinatal Medicine, 2006 * The Human Protection Award (Livsvernprisen) (with Torleiv Ole Rognum), 2007 * Knight First Class of the
Royal Norwegian Order of St. Olav Royal may refer to: People * Royal (name), a list of people with either the surname or given name * A member of a royal family Places United States * Royal, Arkansas, an unincorporated community * Royal, Illinois, a village * Royal, Iowa, a ci ...
, 2010 * Märta Philipson Award for Progress in Pediatrics (University of Stockholm), 2010 * Honorary member of the American Pediatric Society 2011 * American Academy of Pediatrics Landmark Award 2011Bjørnsonprisen for første gong til to nordmenn
''
NRK NRK, an abbreviation of the Norwegian ''Norsk Rikskringkasting AS'', generally expressed in English as the Norwegian Broadcasting Corporation, is the Norwegian government-owned radio and television public broadcasting company, and the largest ...
'', 19 October 2011
* The Bjørnson Prize, 2011 * Nordic Medical Prize, 2012 * Member of the
Norwegian Academy of Science and Letters The Norwegian Academy of Science and Letters ( no, Det Norske Videnskaps-Akademi, DNVA) is a learned society based in Oslo, Norway. Its purpose is to support the advancement of science and scholarship in Norway. History The Royal Frederick Unive ...
, 2013 * Honorary doctorate,
University of Athens The National and Kapodistrian University of Athens (NKUA; el, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών, ''Ethnikó ke Kapodistriakó Panepistímio Athinón''), usually referred to simply as the Univers ...
, 2014Norwegian paediatrician honoured by University of Athens
Royal Ministry of Foreign Affairs The Royal Norwegian Ministry of Foreign Affairs ( Norwegian (Bokmål): ''Det kongelige utenriksdepartement''; Norwegian (Nynorsk): ''Det kongelege utanriksdepartement'') is the foreign ministry of the Kingdom of Norway. It was established on June ...
*Honorary Professor,
Moscow State University M. V. Lomonosov Moscow State University (MSU; russian: Московский государственный университет имени М. В. Ломоносова) is a public research university in Moscow, Russia and the most prestigious ...
, 2014 * Chiesi Prize of Excellence in Neonatology, 2017Prisdryss til professor Ola Didrik Saugstad
/ref> * Erich Saling Perinatal Prize, 2017


References

{{DEFAULTSORT:Saugstad, Ola Didrik 1947 births Living people University of Oslo alumni University of Oslo faculty Oslo University Hospital people Norwegian neuroscientists Norwegian neonatologists Medical ethicists Members of the Norwegian Academy of Science and Letters