O-acetylhomoserine Aminocarboxypropyltransferase
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In
enzymology Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, an ''O''-acetylhomoserine aminocarboxypropyltransferase () is an enzyme that
catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the chemical reaction :''O''-acetyl-L-homoserine + methanethiol \rightleftharpoons L-methionine + acetate Thus, the two substrates of this enzyme are ''O''-acetyl-L-homoserine and methanethiol, whereas its two products are L-methyionine and
acetate An acetate is a salt (chemistry), salt formed by the combination of acetic acid with a base (e.g. Alkali metal, alkaline, Alkaline earth metal, earthy, Transition metal, metallic, nonmetallic or radical Radical (chemistry), base). "Acetate" als ...
. This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is ''O''-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase. Other names in common use include ''O''-acetyl-L-homoserine acetate-lyase (adding methanethiol), O-acetyl-L-homoserine sulfhydrolase, ''O''-acetylhomoserine (thiol)-lyase, ''O''-acetylhomoserine sulfhydrolase, and methionine synthase. This enzyme participates in
methionine metabolism Methionine (symbol Met or M) () is an essential amino acid in humans. As the precursor of other amino acids such as cysteine and taurine, versatile compounds such as SAM-e, and the important antioxidant glutathione, methionine plays a critical ...
and
cysteine metabolism Cysteine metabolism refers to the biological pathways that consume or create cysteine. The pathways of different amino acids and other metabolites interweave and overlap to creating complex systems.cysteine is metabolism creating complex systems ...
.


References

* * * * * * * EC 2.5.1 Enzymes of unknown structure {{2.5-enzyme-stub