National Bio And Agro-Defense Facility
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The National Bio and Agro-Defense Facility (NBAF) is a biosafety level 4 research laboratory in
Manhattan, Kansas Manhattan is a city and county seat of Riley County, Kansas, United States, although the city extends into Pottawatomie County. It is located in northeastern Kansas at the junction of the Kansas River and Big Blue River. As of the 2020 cen ...
, operated by the
United States Department of Agriculture The United States Department of Agriculture (USDA) is the United States federal executive departments, federal executive department responsible for developing and executing federal laws related to farming, forestry, rural economic development, ...
. Slated to open in Summer 2022, the facility is designed to combat biological threats involving human, zoonotic, and foreign animal diseases. The NBAF will be replacing the aging
Plum Island Animal Disease Center Plum Island Animal Disease Center (PIADC) is a United States federal research facility dedicated to the study of foreign animal diseases of livestock. It is part of the Department of Homeland Security Directorate for Science and Technology, an ...
(PIADC) on
Plum Island, New York Plum Island is an island in the town of Southold in Suffolk County, New York. The island is situated in Gardiners Bay, east of Orient Point, off the eastern end of the North Fork coast of Long Island. It is about long and wide at its wid ...
. The primary research tenants of the facility will be the Agriculture Research Service (USDA-ARS) and Animal Plant Health Inspection Service, Veterinary Services (USDA-APHIS-VS). Construction on the facility officially began in May 2015, and was scheduled to be completed by May 2021. The ongoing
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, however, has delayed scheduled commissioning to October 2021, followed by further delays to Spring, and, subsequently, Summer 2022. Operations will be fully transferred from the Plum Island facility by 2023. When fully operational, the facility will employ between 250 and 350 people. The facility is a constituent member of the
Biosafety Level 4 Zoonotic Laboratory Network The Biosafety Level 4 Zoonotic Laboratory Network is an international consortium of Biosafety Level 4 research laboratories. Its members are * National Centre for Foreign Animal Disease (Canada) * National Bio and Agro-Defense Facility (United Stat ...
, and is currently led by Alfonso Clavijo.


Background

The NBAF was initially proposed because the prior facility on Plum Island was considered inadequate by the Department of Homeland Security, citing its size, and lack of Biosafety Level 4 (BSL-4) capabilities. The new facility will research and develop countermeasures to combat high-consequence biological threats involving human, zoonotic (i.e., transmitted from animals to humans), and foreign animal diseases. Included among the diseases to be studied at the research lab are
foot-and-mouth disease Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever lasting two to six days, followe ...
,
classical swine fever Classical swine fever (CSF) or hog cholera (also sometimes called pig plague based on the German word ) is a highly contagious disease of swine ( Old World and New World pigs). It has been mentioned as a potential bioweapon. Clinical signs ...
,
African swine fever ''African swine fever virus'' (ASFV) is a large, double-stranded DNA virus in the '' Asfarviridae'' family. It is the causative agent of African swine fever (ASF). The virus causes a hemorrhagic fever with high mortality rates in domestic pigs; ...
and
contagious bovine pleuropneumonia Contagious bovine pleuropneumonia (CBPP – also known as lung plague), is a contagious bacterial disease that afflicts the lungs of cattle, buffalo, zebu, and yaks. It is caused by the bacterium ''Mycoplasma mycoides'', and the symptoms are pneu ...
. Approximately 10% of the facility will be used for BSL-4 level research.


Site selection

DHS decided to locate the NBAF in Manhattan, Kansas, after a multi-year process. Out of 29 original sites considered in 2006, the agency selected six finalists in 2008: *
University of Georgia , mottoeng = "To teach, to serve, and to inquire into the nature of things.""To serve" was later added to the motto without changing the seal; the Latin motto directly translates as "To teach and to inquire into the nature of things." , establ ...
/South Milledge Ave –
Athens, Georgia Athens, officially Athens–Clarke County, is a consolidated city-county and college town in the U.S. state of Georgia. Athens lies about northeast of downtown Atlanta, and is a satellite city of the capital. The University of Georgia, the sta ...
*
Kansas State University Kansas State University (KSU, Kansas State, or K-State) is a public land-grant research university with its main campus in Manhattan, Kansas, United States. It was opened as the state's land-grant college in 1863 and was the first public instit ...
– Manhattan, Kansas * Flora Industrial Park –
Madison County, Mississippi Madison County is a county located in the U.S. state of Mississippi. As of the 2010 census, the population was 95,203. The county seat is Canton. The county is named for U.S. President James Madison. Madison County is part of the Jackson, ...
*
Plum Island Animal Disease Center Plum Island Animal Disease Center (PIADC) is a United States federal research facility dedicated to the study of foreign animal diseases of livestock. It is part of the Department of Homeland Security Directorate for Science and Technology, an ...
New York New York most commonly refers to: * New York City, the most populous city in the United States, located in the state of New York * New York (state), a state in the northeastern United States New York may also refer to: Film and television * '' ...
* Umstead Research Farm –
Granville County, North Carolina Granville County is a county located on the northern border of the U.S. state of North Carolina. As of the 2020 census, the population was 60,992. Its county seat is Oxford. Granville County encompasses Oxford, NC Micropolitan Statistical Are ...
* Texas Research Park –
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Before the selection of the site, several rural advocacy groups, such as the
National Grange The Grange, officially named The National Grange of the Order of Patrons of Husbandry, is a social organization in the United States that encourages families to band together to promote the economic and political well-being of the community and ...
, spoke out against the idea of locating the facility on the mainland. In addition, groups formed in Manhattan; Athens, Georgia; and
Butner, North Carolina Butner is a town in Granville County, North Carolina, United States. The population was 8,397 as of the 2020 census. Butner was managed by the state of North Carolina from 1947 through 2007. History A bill passed by the North Carolina General ...
to oppose the laboratory's proposed location in those cities. By memo dated December 4, 2008, the Department of Homeland Security named the Kansas site as the preferred location for the NBAF. On January 16, 2009, the record of decision was published in the ''
Federal Register The ''Federal Register'' (FR or sometimes Fed. Reg.) is the official journal of the federal government of the United States that contains government agency rules, proposed rules, and public notices. It is published every weekday, except on feder ...
''. After the Manhattan location was finalized in 2009, the
Government Accountability Office The U.S. Government Accountability Office (GAO) is a legislative branch government agency that provides auditing, evaluative, and investigative services for the United States Congress. It is the supreme audit institution of the federal govern ...
questioned the choice of location in a July 2010 draft report, because it is located on the mainland U.S. unlike the current Plum Island facility. This led to a further "site-specific" study of the facility's safety, issued by DHS in 2012.


Risk assessments

Plum Island is the only research facility currently studying
foot-and-mouth disease Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever lasting two to six days, followe ...
(FMD) in the U.S. In 2008, the Government Accountability Office (GAO) was asked to evaluate the evidence DHS used to support its determinations that FMD work can be done safely on the U.S. mainland, whether an island location provides any additional protection over and above that provided by modern high containment laboratories on the mainland, and the economic consequences of an FMD outbreak on the U.S. mainland. Because of concerns raised by the GAO in 2010, Congress instructed DHS to complete a "site-specific biosafety and biosecurity risk assessment." It also directed the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
to appoint a committee of the
National Research Council National Research Council may refer to: * National Research Council (Canada), sponsoring research and development * National Research Council (Italy), scientific and technological research, Rome * National Research Council (United States), part of ...
(NRC) to conduct an independent evaluation of this site-specific risk analysis to determine its adequacy and validity. Congress would not release construction funds until these were completed and evaluated. DHS completed the requisite site-specific risk analysis (SSRA) in March 2012, and the NRC committee issued its evaluation of the SSRA in June 2012.


Site construction

The facility is under construction. Preliminary clearing and grading of the proposed site began in 2010, construction on the site's power plant began in 2013, and construction of the lab began in 2015. On January 2, 2013, the Department of Homeland Security accepted a transfer of land from the State of Kansas for the site of the facility. In March 2013, a contract was awarded for the construction of a central utility plant for the NBAF. An official
groundbreaking Groundbreaking, also known as cutting, sod-cutting, turning the first sod, or a sod-turning ceremony, is a traditional ceremony in many cultures that celebrates the first day of construction for a building or other project. Such ceremonies are o ...
ceremony for construction of the power plant was held on May 28, 2013. The federal government budgeted $440 million for construction and related work on the NBAF under the Consolidated Appropriations Act of 2014, signed into law on January 17, 2014. President
Barack Obama Barack Hussein Obama II ( ; born August 4, 1961) is an American politician who served as the 44th president of the United States from 2009 to 2017. A member of the Democratic Party, Obama was the first African-American president of the U ...
included an additional $300 million for construction in his proposed 2015 budget, constituting the final installment of federal construction spending for the facility. This funding was secured when President Obama signed into law the
Department of Homeland Security Appropriations Act, 2015 The Department of Homeland Security Appropriations Act, 2014 (, {{uspl, 114, 4) is an appropriations bill that was introduced into the United States House of Representatives during the 114th United States Congress. The bill would appropriate mo ...
, on March 3, 2015. A groundbreaking ceremony for construction on the full facility was held on May 27, 2015. It was attended by Kansas Senator
Pat Roberts Charles Patrick Roberts (born April 20, 1936) is a retired American politician and journalist who served as a United States senator from Kansas from 1997 to 2021. A member of the Republican Party, Roberts served 8 terms in the U.S. House of Re ...
, Kansas Governor
Sam Brownback Samuel Dale Brownback (born September 12, 1956) is an American attorney, politician, diplomat, and member of the Republican Party (United States), Republican Party who served as the United States Ambassador-at-Large for International Religious Fr ...
, U.S. Secretary of Agriculture
Tom Vilsack Thomas James Vilsack (; born December 13, 1950) is an American politician serving as the 32nd United States Secretary of Agriculture in the Biden administration. He previously served in the role from 2009 to 2017 during the Obama administration. ...
, and Homeland Security Secretary
Jeh Johnson Jeh Charles Johnson ( "Jay"; born September 11, 1957) is an American lawyer and former government official. He was United States Secretary of Homeland Security from 2013 to 2017. From 2009 to 2012, Johnson was the general counsel of the Departm ...
. In 2019 the
Department of Homeland Security The United States Department of Homeland Security (DHS) is the U.S. federal executive department responsible for public security, roughly comparable to the interior or home ministries of other countries. Its stated missions involve anti-terr ...
shed its interest in the project, and agreed to transfer operating responsibility of the facility once completed to the Department of Agriculture. DHS will remain in charge of the remainder of construction.


References


External links

* {{U.S. biological defense United States Department of Homeland Security Buildings and structures in Riley County, Kansas Biosafety level 4 laboratories Manhattan, Kansas