NADH dehydrogenase is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...
that converts
nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an ...
(NAD) from its reduced form (NADH) to its oxidized form (NAD
+). Members of the NADH dehydrogenase family and analogues are commonly
systematically named using the format ''NADH:acceptor oxidoreductase''.
The
chemical reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and break ...
these enzymes
catalyze are generally represented with the follow equation;
: NADH + H
+ + acceptor NAD
+ + reduced acceptor
NADH dehydrogenase is a
flavoprotein that contains iron-sulfur centers.
NADH dehydrogenase is used in the electron transport chain for generation of ATP.
The EC term
NADH dehydrogenase (quinone)
Respiratory complex I, (also known as NADH:ubiquinone oxidoreductase, Type I NADH dehydrogenase and mitochondrial complex I) is the first large protein complex of the respiratory chains of many organisms from bacteria to humans. It catalyzes the ...
(EC 1.6.5.11) is defined for NADH dehydrogenases that use a
quinone
The quinones are a class of organic compounds that are formally "derived from aromatic compounds benzene.html" ;"title="uch as benzene">uch as benzene or naphthalene] by conversion of an even number of –CH= groups into –C(=O)– groups with ...
(excluding ubiquinone) as the acceptor. The EC term
NADH dehydrogenase (ubiquinone)
Respiratory complex I, (also known as NADH:ubiquinone oxidoreductase, Type I NADH dehydrogenase and mitochondrial complex I) is the first large protein complex of the respiratory chains of many organisms from bacteria to humans. It catalyzes the ...
(EC 7.1.1.2) is defined for those with ubiquinone as the acceptor.
References
External links
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EC 1.6.99
sr:NADH dehidrogenaza