19-Noretiocholanolone, also known as 5β-estran-3α-ol-17-one, is a

metabolite In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...

nandrolone Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin). Nandrolon ...

(19-nortestosterone) and

bolandione Bolandione, also known as 19-norandrostenedione, as well as 19-norandrost-4-en-3,17-dione or estr-4-ene-3,17-dione, is a precursor (chemistry), precursor of the anabolic-androgenic steroid (AAS) nandrolone (19-nortestosterone). Until 2005, boland ...

(19-norandrostenedione) that is formed by

5α-reductase 5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in three metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism. There are three isozymes of ...

. It is on the list of substances prohibited by the

World Anti-Doping Agency The World Anti-Doping Agency (WADA; french: Agence mondiale antidopage, AMA) is a foundation initiated by the International Olympic Committee based in Canada to promote, coordinate, and monitor the fight against drugs in sports. The agency's key ...

since it is a detectable metabolite of nandrolone, an

anabolic-androgenic steroid Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone (medication), testosterone as well as synthetic androgens that are structurally related ...

(AAS). Traces of 19-noretiocholanolone may be naturally present in human

urine Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excretion, excreted from the body through the urethra. Cel ...

. Consumption of boar meat, liver, kidneys and heart have been found to increase urinary 19-noretiocholanolone output.

References

{{DEFAULTSORT:Noretiocholanolone, 19- 5α-Reduced steroid metabolites Secondary alcohols Estranes Human drug metabolites Ketones World Anti-Doping Agency prohibited substances

See also

References